Evidence map›Paper›PMID 31719541›Full record

ArticleScientific reports2019

Effects of Eucalypt Plant Monoterpenes on Koala (Phascolarctos Cinereus) Cytokine Expression In Vitro.

Caroline Marschner, Mark B Krockenberger, Damien P Higgins

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Polyphasic Characterisation ofMicroorganisms · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caroline MarschnerSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, 2006, NSW, Australia. cmar3346@uni.sydney.edu.au.
Mark B KrockenbergerSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, 2006, NSW, Australia.ORCID http://orcid.org/0000-0002-8168-4795
Damien P HigginsSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, 2006, NSW, Australia.ORCID http://orcid.org/0000-0003-1215-6523
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protective immunity is crucial for survival of any species, though the koala as a specialist feeder adapted to an exclusive diet of eucalypts that contain plant secondary metabolites of varying toxicity and of immunomodulatory property. Being constantly exposed to such dietary chemicals it raises the question of their immune effects in a specialist eucalypt feeder. This study demonstrates that natural levels of circulating eucalypt plant secondary metabolites have dose dependent in vitro effects on cytokine expression of koala peripheral blood mononuclear cells, suggesting a potential trade-off of reduced function in multiple arms of the immune system associated with koala's use of its specialized dietary niche.

Indexed as

AnimalsCymenesCytokinesEucalyptolEucalyptusFemaleLeukocytes, MononuclearMaleMonoterpenesPhascolarctidaeUp-Regulation4-cymeneCymenesCytokinesEucalyptolMonoterpenes

Identifiers

PMID31719541
PMCPMC6851357
OpenAlexW2987094175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.