Evidence map›Paper›PMID 31719527›Full record

Trial reportTranslational psychiatry2019

Acute anxiety and autonomic arousal induced by CO

George Savulich, Frank H Hezemans, Sophia van Ghesel Grothe, Jessica Dafflon, Norah Schulten, Annette B Brühl, Barbara J Sahakian, Trevor W Robbins

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Rebreathing during CPAP therapy and its implications in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  7. Hypercapnia Reduces Perceived Heat Pain in Healthy Subjects.European journal of pain (London, England) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Multiscale neural signatures of major depressive, anxiety, and stress-related disorders.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Altered chemosensitivity to COPhysiological reports · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

George SavulichDepartment of Psychiatry, University of Cambridge, School of Clinical Medicine, Cambridge, UK.ORCID http://orcid.org/0000-0002-6513-5454
Frank H HezemansBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0092-3289
Sophia van Ghesel GrotheBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
Jessica DafflonBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
Norah SchultenBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
Annette B BrühlBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-4704-4986
Barbara J SahakianDepartment of Psychiatry, University of Cambridge, School of Clinical Medicine, Cambridge, UK.
Trevor W RobbinsBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK. twr2@cam.ac.uk.ORCID http://orcid.org/0000-0003-0642-5977

Funding

Medical Research Council G0001354Medical Research Council G1000183Wellcome Trust
6 · The paper itself

Abstract

Acute anxiety impacts cognitive performance. Inhalation of air enriched with carbon dioxide (CO

Indexed as

Administration, InhalationAdultAnxietyAutonomic Nervous SystemBlood PressureCarbon DioxideCross-Over StudiesExecutive FunctionFemaleHealthy VolunteersHeart RateHumansMaleMemory, Short-TermNeuropsychological TestsPanicCarbon Dioxide

Identifiers

PMID31719527
PMCPMC6851177

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.