Evidence map›Paper›PMID 31719253›Full record

ArticleNeural regeneration research2020

Neonatal ketamine exposure-induced hippocampal neuroapoptosis in the developing brain impairs adult spatial learning ability.

Dan Lyu, Ning Tang, Andrew W Womack, Yong-Jin He, Qing Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dan LyuDepartment of Pain Management, Tianjin First Center Hospital, Tianjin, China; Department of Psychology, College of Science, University of Texas at Arlington, Arlington, TX, USA.
Ning TangDepartment of Psychology, College of Science, University of Texas at Arlington, Arlington, TX, USA; Reproductive Medicine Center, the 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong Province, China.
Andrew W WomackDepartment of Psychology, College of Science, University of Texas at Arlington, Arlington, TX, USA.
Yong-Jin HeDepartment of Pain Management, Tianjin First Center Hospital, Tianjin, China.
Qing LinDepartment of Psychology, College of Science, University of Texas at Arlington, Arlington, TX, USA.
The University of Texas at Arlington · USTianjin First Center Hospital · CNTianjin Medical University · CN

Funding

Spinal Cord-Mediated Acute Neurogenic InflammationR01NS040723 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI LIN, QING · 2001 to 2010
$2.3M
NINDS NIH HHS R01 NS040723
6 · The paper itself

Abstract

Ketamine exposure can lead to selective neuroapoptosis in the developing brain. p

Indexed as

caspase-3developmental neuroapoptosishippocampusketamineMorris water mazeN-methyl-D-aspartate acid receptorsp66 ShcAspatial learning

Identifiers

PMID31719253
PMCPMC6990767
OpenAlexW2988078783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.