Evidence map›Paper›PMID 31719208›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Definitive demonstration by synthesis of genome annotation completeness.

Paul R Jaschke, Gabrielle A Dotson, Kay S Hung, Diane Liu, Drew Endy

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Genome synthesis, assembly, and rebooting of therapeutically useful high G+C% mycobacteriophages.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. An Improved Method for Eliminating or Creating Intragenic Bacterial Promoters.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Suppression of Grape White Rot Caused byPathogens (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul R JaschkeDepartment of Molecular Sciences, Macquarie University, Sydney, NSW 2109, Australia; paul.jaschke@mq.edu.au endy@stanford.edu.ORCID 0000-0003-2359-1301
Gabrielle A DotsonBioengineering Department, Stanford University, Stanford, CA 94305.ORCID 0000-0001-6624-5332
Kay S HungBioengineering Department, Stanford University, Stanford, CA 94305.
Diane LiuBioengineering Department, Stanford University, Stanford, CA 94305.
Drew EndyBioengineering Department, Stanford University, Stanford, CA 94305 paul.jaschke@mq.edu.au endy@stanford.edu.ORCID 0000-0001-6952-8098

Funding

University of Michigan Training Program in Genomic ScienceT32HG000040 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sebastian Zoellner · 1995 to 2026
$16.4M
NHGRI NIH HHS T32 HG000040
6 · The paper itself

Abstract

We develop a method for completing the genetics of natural living systems by which the absence of expected future discoveries can be established. We demonstrate the method using bacteriophage øX174, the first DNA genome to be sequenced. Like many well-studied natural organisms, closely related genome sequences are available-23

Indexed as

Genome, ViralOpen Reading FramesBase SequenceCodonColiphagesConserved SequenceDirected Molecular EvolutionGene Expression Regulation, ViralGenes, EssentialGenomicsMicroorganisms, Genetically-ModifiedMolecular Sequence AnnotationMutationViral ProteinsCodonViral Proteinscleanomicsgene discoveryreverse genomicssynthetic biologysynthetic genomics

Identifiers

PMID31719208
PMCPMC6883844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.