Evidence map›Paper›PMID 31719050›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2020

Coaltered

Jashodeep Datta, J Joshua Smith, Walid K Chatila, John C McAuliffe, Cyriac Kandoth, Efsevia Vakiani, Timothy L Frankel, Karuna Ganesh, Isaac Wasserman, Marla Lipsyc-Sharf and 18 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 89 citations in OpenAlex.

  1. Trial
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  14. Lung metastases.Nature reviews. Disease primers · 2025
    Review
  15. Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?Journal of experimental & clinical cancer research : CR · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. FROM ONCOLOGIST TO SURGEON - GENETICS IN COLORECTAL METASTASIS FOR SURGEONS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 1 institution in 1 country.

Jashodeep Datta *Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. jash.datta@med.miami.edu dangelim@mskcc.org smithj5@mskcc.org.ORCID 0000-0002-5052-7586
J Joshua Smith *Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. jash.datta@med.miami.edu dangelim@mskcc.org smithj5@mskcc.org.ORCID 0000-0003-2538-5456
Walid K Chatila *Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
John C McAuliffeDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Cyriac KandothMarie-Josée & Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-1345-3573
Efsevia VakianiDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Timothy L FrankelDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Karuna GaneshHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Isaac WassermanDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-6955-0567
Marla Lipsyc-SharfDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-4071-6383
Jose GuillemDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Garrett M NashDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Philip B PatyDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Martin R WeiserDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Leonard B SaltzDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-8353-4670
Michael F BergerHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
William R JarnaginDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Vinod BalachandranDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-0909-8855
T Peter KinghamDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Nancy E KemenyDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Andrea CercekDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Julio Garcia-AguilarDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Barry S TaylorHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Agnes VialeMarie-Josée & Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Rona YaegerDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
David B SolitHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Nikolaus SchultzHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Michael I D'AngelicaDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. jash.datta@med.miami.edu dangelim@mskcc.org smithj5@mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
Investigating L1CAM-dependent stem cell regeneration in metastasisK08CA230213 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GANESH, KARUNA · 2018 to 2022
$1.3M
NCATS NIH HHS UL1 TR002736NCI NIH HHS K08 CA230213NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeWe aimed to investigate genomic correlates underlying extremes of survivorship in metastatic colorectal cancer and their applicability in informing survival in distinct subsets of patients with metastatic colorectal cancer. EXPERIMENTAL

designWe examined differences in oncogenic somatic alterations between metastatic colorectal cancer cohorts demonstrating extremes of survivorship following complete metastasectomy: ≤2-year (

resultsIn the extremes-of-survivorship cohort, significant co-occurrence of

conclusionsGenomic analysis of extremes of survivorship following colorectal cancer metastasectomy identifies a prognostic role for coaltered

Indexed as

MutationBiomarkers, TumorCohort StudiesColorectal NeoplasmsFemaleFollow-Up StudiesGTP PhosphohydrolasesHigh-Throughput Nucleotide SequencingHumansMaleMembrane ProteinsMiddle AgedNeoplasm MetastasisPrognosisProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)Biomarkers, TumorBRAF protein, humanGTP PhosphohydrolasesKRAS protein, humanMembrane ProteinsNRAS protein, humanProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)TP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID31719050
PMCPMC7056517
OpenAlexW2987342757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.