Evidence map›Paper›PMID 31719049›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2020

Comprehensive Transcriptome Profiling of Cryptic

Jenny L Smith, Rhonda E Ries, Tiffany Hylkema, Todd A Alonzo, Robert B Gerbing, Marianne T Santaguida, Lisa Eidenschink Brodersen, Laura Pardo, Carrie L Cummings, Keith R Loeb and 14 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Extramedullary Relapse ofInternational journal of molecular sciences · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Effects of transcription factorAnnals of surgical treatment and research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 2 countries.

Jenny L SmithClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. jlsmith3@fredhutch.org smeshinc@fhcrc.org.
Rhonda E RiesClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.ORCID 0000-0002-3702-7923
Tiffany HylkemaClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Todd A AlonzoChildren's Oncology Group, Monrovia, California.
Robert B GerbingChildren's Oncology Group, Monrovia, California.
Marianne T SantaguidaNotable Laboratories, San Francisco, California.
Lisa Eidenschink BrodersenHematologics Inc, Seattle, Washington.
Laura PardoClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Carrie L CummingsClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Keith R LoebClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Quy LeClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Suzan ImrenClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Amanda R LeontiClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Alan S GamisChildren's Mercy Cancer Center, Kansas City, Missouri.
Richard AplencDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
E Anders KolbNemours Alfred I. duPont Hospital for Children, Wilmington, Delaware.
Jason E FarrarUAMS, Arkansas Children's Hospital, Little Rock, Arkansas.ORCID 0000-0003-2148-5839
Timothy J TricheVan Andel Research Institute, Grand Rapids, Michigan.
Cu NguyenCenter for Biomedical Informatics and Information Technology, NCI, Rockville, Maryland.
Daoud MeerzamanCenter for Biomedical Informatics and Information Technology, NCI, Rockville, Maryland.
Michael R LokenHematologics Inc, Seattle, Washington.
Vivian G OehlerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Hamid BolouriInformatics and Computational Biology, Allen Institute, Seattle, Washington.
Soheil MeshinchiClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. jlsmith3@fredhutch.org smeshinc@fhcrc.org.
Fred Hutch Cancer Center · USChildren's Oncology Group · CHAnthem (United States) · USCenter for Information Technology · USAlfred I. duPont Hospital for Children · USAllen Institute · USArkansas Children's Hospital · USChildren's Hospital of Philadelphia · USChildren's Mercy Hospital · USNotable Labs (United States) · USVan Andel Institute · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Biology/prognostic implications of Flt3 mutations in AMLR01CA114563 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MESHINCHI, SOHEIL · 2005 to 2016
$4.4M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENCI NIH HHS P30 CA015704NCI NIH HHS R01 CA114563NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

purposeA cryptic inv(16)(p13.3q24.3) encoding the EXPERIMENTAL

designAvailable RNA from children and young adults with

resultsThe

conclusionsThe

Indexed as

Gene Expression ProfilingMutationAdultBiomarkers, TumorCD56 AntigenChild, PreschoolFemaleFollow-Up StudiesHumansInfantInfant, NewbornLeukemia, Myeloid, AcuteMaleMicroRNAsMiddle AgedOncogene Proteins, FusionBiomarkers, TumorCBFA2T3-GLIS2 fusion protein, humanCD56 AntigenGABRE protein, humanMicroRNAsNCAM1 protein, humanOncogene Proteins, FusionReceptors, GABA-ARNA, Messenger

Identifiers

PMID31719049
PMCPMC7002196
OpenAlexW2987877754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.