Evidence map›Paper›PMID 31718659›Full record

ArticleMalaria journal2019

Repeated mosquito net distributions, improved treatment, and trends in malaria cases in sentinel health facilities in Papua New Guinea.

Daniela Rodriguez-Rodriguez, Seri Maraga, Lina Lorry, Leanne J Robinson, Peter M Siba, Ivo Mueller, Justin Pulford, Amanda Ross, Manuel W Hetzel

Abstract read
In one paragraph

Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniela Rodriguez-RodriguezSwiss Tropical and Public Health Institute, Basel, Switzerland.
Seri MaragaPapua New Guinea Institute of Medical Research, Goroka and Madang, Papua New Guinea.
Lina LorryPapua New Guinea Institute of Medical Research, Goroka and Madang, Papua New Guinea.
Leanne J RobinsonPapua New Guinea Institute of Medical Research, Goroka and Madang, Papua New Guinea.
Peter M SibaPapua New Guinea Institute of Medical Research, Goroka and Madang, Papua New Guinea.
Ivo MuellerWalter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
Justin PulfordLiverpool School of Tropical Medicine, Liverpool, UK.
Amanda RossSwiss Tropical and Public Health Institute, Basel, Switzerland.
Manuel W HetzelSwiss Tropical and Public Health Institute, Basel, Switzerland. manuel.hetzel@swisstph.ch.ORCID http://orcid.org/0000-0002-5285-3254

Funding

Understanding, tracking and eliminating malaria transmission in the Asia - Pacific RegionU19AI129392 · NIAID · WALTER AND ELIZA HALL INST MEDICAL RES · PI Ivo J Mueller, Leanne Robinson · 2017 to 2026
$7.1M
NIAID NIH HHS U19 AI129392The Global Fund to Fight AIDS, Tuberculosis and Malaria Round 8 malaria grant
6 · The paper itself

Abstract

backgroundLong-lasting insecticidal nets (LLIN), improved diagnosis and artemisinin-based combination therapy (ACT) have reduced malaria prevalence in Papua New Guinea since 2008. Yet, national incidence trends are inconclusive due to confounding effects of the scale-up of rapid diagnostic tests, and inconsistencies in routine reporting.

methodsMalaria trends and their association with LLIN and ACT roll-out between 2010 and 2014 in seven sentinel health facilities were analysed. The analysis included 35,329 fever patients. Intervention effects were estimated using regression models.

resultsMalaria incidence initially ranged from 20 to 115/1000 population; subsequent trends varied by site. Overall, LLIN distributions had a cumulative effect, reducing the number of malaria cases with each round (incidence rate ratio ranging from 0.12 to 0.53 in five sites). No significant reduction was associated with ACT introduction. Plasmodium falciparum remained the dominant parasite in all sentinel health facilities. Resurgence occurred in one site in which a shift to early and outdoor biting of anophelines had previously been documented.

conclusionsLLINs, but not ACT, were associated with reductions of malaria cases in a range of settings, but sustainability of the gains appear to depend on local factors. Malaria programmes covering diverse transmission settings such as Papua New Guinea must consider local heterogeneity when choosing interventions and ensure continuous monitoring of trends.

Indexed as

Mosquito ControlArtemisininsCommunicable Disease ControlDrug CombinationsHealth FacilitiesHumansIncidenceInsecticide-Treated BednetsLactonesMalariaPapua New GuineaPlasmodiumartemisinArtemisininsDrug CombinationsLactonesArtemisinin-based combination therapyIncidenceMalariaPlasmodium falciparumPlasmodium vivaxVector control

Identifiers

PMID31718659
PMCPMC6852945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.