SynthesisJournal of orthopaedic surgery and research2019
Debridement, antibiotics, and implant retention for periprosthetic knee infections: a pooling analysis of 1266 cases.
Synthesis in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Differences of microbial growth and biofilm formation among periprosthetic joint infection-causing species: an animal study.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- The value of repeated debridement, antibiotics, and implant retention (DAIR) for early periprosthetic joint infection.Journal of bone and joint infection · 2025Article
- Debridement, antimicrobial therapy, and implant retention (DAIR) as curative strategy for acute periprosthetic hip and knee infections: a position paper of the European Bone & Joint Infection Society (EBJIS).Journal of bone and joint infection · 2025Article
- DAIR for periprosthetic joint infections-One week to save the joint?Arthroplasty (London, England) · 2024Article
- Debridement, antibiotics and implant retention (DAIR) following hip and knee arthroplasty: results and findings of a multidisciplinary approach from a non-specialist prosthetic infection centre.Annals of the Royal College of Surgeons of England · 2024Article
- The Economics of Revision Arthroplasty for Periprosthetic Joint Infection.Arthroplasty today · 2023Article
- Predictors of Treatment Success After Periprosthetic Joint Infection: 24-Month Follow up From a Multicenter Prospective Observational Cohort Study of 653 Patients.Open forum infectious diseases · 2022Article
- Contemporary outcomes of debridement, antibiotics and implant retention in knee arthroplasty.Annals of joint · 2022Review
- Comparison of the success rate after debridement, antibiotics and implant retention (DAIR) for periprosthetic joint infection among patients with or without a sinus tract.BMC musculoskeletal disorders · 2021Article
- Management strategies for prosthetic joint infection: long-term infection control rates, overall survival rates, functional and quality of life outcomes.EFORT open reviews · 2021Review
- Biofilm-Related Infections in Gram-Positive Bacteria and the Potential Role of the Long-Acting Agent Dalbavancin.Frontiers in microbiology · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe debridement, antibiotics, and implant retention (DAIR) procedure is an established therapeutic option for periprosthetic knee infections (PKI). However, the efficacy and the indication for this procedure are still controversial.
methodsAll the relevant literatures were systematically reviewed and analyzed. The present study aimed to assess the success rate of DAIR in the management of PKI, identify the factors associated with prognosis of DAIR, and establish a simple algorithm for predicting a high success rate of DAIR.
resultsTotally, 33 studies with 1266 cases were included. The overall success rate following DAIR in the management of PKI was 57.11%. In the subgroup analyses, the factors of "the time from symptoms to debridement was < 3 weeks" and "the bacterial species other than methicillin-resistant Staphylococcus aureus" significantly improved the success rate of DAIR and thus were defined as the major criteria. The statistically insignificant factors of "the open debridement and liner exchange" and "the comorbidity of rheumatoid arthritis" were set as the minor criteria. The success rate of DAIR for PKI meeting all the major criteria and no less than one minor criterion was 80.98%, which was significantly higher than the overall success rate of DAIR (p < 0.05).
conclusionPKI cases meeting two major criteria and no less than one minor criterion may confer a high success rate of DAIR. This simple algorithm may contribute to identifying the appropriate PKI patient for DAIR treatment and predicting the prognosis of DAIR.
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