Evidence map›Paper›PMID 31718578›Full record

ArticleBMC infectious diseases2019

The 2017-2018 influenza season in Bucharest, Romania: epidemiology and characteristics of hospital admissions for influenza-like illness.

Anca Drăgănescu, Oana Săndulescu, Dragoș Florea, Ovidiu Vlaicu, Anca Streinu-Cercel, Dan Oțelea, Monica Luminița Luminos, Victoria Aramă, Sorin Abrudan, Adrian Streinu-Cercel and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anca DrăgănescuChildren X Department, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Oana SăndulescuAdults II Department, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania. oana.sandulescu@umfcd.ro.ORCID http://orcid.org/0000-0002-2586-4070
Dragoș FloreaMolecular Diagnosis Laboratory, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Ovidiu VlaicuMolecular Diagnosis Laboratory, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Anca Streinu-CercelAdults II Department, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Dan OțeleaMolecular Diagnosis Laboratory, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Monica Luminița LuminosChildren X Department, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Victoria AramăDepartment of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Sorin AbrudanMedical CEE, Sanofi Pasteur, Bucharest, Romania.
Adrian Streinu-CercelAdults II Department, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Daniela PițigoiCompartment for Surveillance and Prevention of Healthcare-associated Infections, National Institute for Infectious Diseases 'Prof. Dr. Matei Balş', Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RONational Institute of Research and Development for Biological Sciences · RO

Funding

Foundation for Influenza Epidemiology GIHSN grant 2017/18
6 · The paper itself

Abstract

backgroundSeasonal influenza causes a considerable burden to healthcare services every year. To better measure the impact of severe influenza cases in Romania, we analyzed active surveillance data collected during the 2017-2018 season from patients admitted for influenza-like illness (ILI) at a tertiary care hospital in Bucharest.

methodsPatients admitted for acute ILI were included if they were resident in the Bucharest-Ilfov region, had been hospitalized for at least 24 h, and had onset of symptoms within 7 days before admission. Patient demographics, healthcare use, vaccination status, and outcome data were collected by questionnaire or by searching clinical records. Respiratory swabs were also obtained from each patient to confirm influenza A (A/H1 and A/H3 subtypes) or influenza B (Yamagata and Victoria lineages) infection by real-time reverse-transcription polymerase chain reaction assay.

resultsThe study included 502 patients, many (45.2%) of whom were aged < 5 years. Overall, 108 patients (21.5%) had one or more comorbidities. Seventeen adults aged 18-64 years (3.4%) had been vaccinated against influenza. Patients were hospitalized for a median of 5 days and most (90.4%) were prescribed antiviral treatment. More than one-half of the patients (n = 259, 51.6%) were positive for influenza. Most influenza cases were caused by B viruses (172/259, 66.4%), which were mostly of the B/Yamagata lineage (85 of 94 characterized, 90.4%). Most of the subtyped A viruses were A/H1 (59/74, 79.7%). A/H1 viruses were frequently detected in influenza-positive admissions throughout the 2017-2018 season, whereas the predominant B/Yamagata viruses were detected around the middle of the season, with a peak in cases at week 7 of 2018. Eleven patients were admitted to an intensive care unit; of these, one patient with confirmed B/Yamagata infection died.

conclusionsThese results show that seasonal influenza results in considerable hospitalization in Bucharest-Ilfov, Romania and suggest vaccine coverage should be extended, especially to the youngest age groups. The data from this study should help inform and optimize national influenza healthcare policies.

Indexed as

AdolescentAdultAgedAlphainfluenzavirusCardiovascular DiseasesChildChild, PreschoolFemaleHospitalizationHumansInfantInfant, NewbornInfluenza B virusInfluenza, HumanInfluenza VaccinesMaleInfluenza VaccinesChildrenComorbidityEpidemiologyHospitalizationInfluenzaOlder adultsRomania

Identifiers

PMID31718578
PMCPMC6852761
OpenAlexW2987415689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.