Evidence map›Paper›PMID 31718444›Full record

ArticleJournal of the American Heart Association2019

Cardiomyocyte-Specific

Karthikeyan Thirugnanam, Stephanie M Cossette, Qiulun Lu, Shreya R Chowdhury, Leanne M Harmann, Ankan Gupta, Andrew D Spearman, Dmitry L Sonin, Michelle Bordas, Suresh N Kumar and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Communications between macrophages and cardiomyocytes.Cell communication and signaling : CCS · 2023
    Review
  6. Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Cardiomyocyte-SpecificJournal of the American Heart Association · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Karthikeyan ThirugnanamDivision of Neonatology Department of Pediatrics Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Stephanie M CossetteDivision of Neonatology Department of Pediatrics Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Qiulun LuCenter for Molecular and Translational Medicine Georgia State University Atlanta GA.
Shreya R ChowdhuryObstetrics and Gynecology Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Leanne M HarmannDivision of Cardiovascular Medicine Department of Cell Biology, Neurobiology and Anatomy Cardiovascular Center Clinical and Translational Science Institute Medical College of Wisconsin Milwaukee WI.
Ankan GuptaDivision of Neonatology Department of Pediatrics Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Andrew D SpearmanDivision of Cardiology, Department of Pediatrics, Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Dmitry L SoninAlmazov National Medical Research Centre St.-Petersburg Russia.
Michelle BordasDivision of Neonatology Department of Pediatrics Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Suresh N KumarDivision of Pediatric Pathology Department of Pathology Medical College of Wisconsin Milwaukee WI.
Amy Y PanQuantitative Health Sciences Department of Pediatrics Medical College of Wisconsin Milwaukee WI.
Pippa M SimpsonQuantitative Health Sciences Department of Pediatrics Medical College of Wisconsin Milwaukee WI.
Jennifer L StrandeDivision of Cardiovascular Medicine Department of Cell Biology, Neurobiology and Anatomy Cardiovascular Center Clinical and Translational Science Institute Medical College of Wisconsin Milwaukee WI.
Erin BishopObstetrics and Gynecology Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Ming-Hui ZouCenter for Molecular and Translational Medicine Georgia State University Atlanta GA.
Ramani RamchandranDivision of Neonatology Department of Pediatrics Developmental Vascular Biology Program, Children's Research Institute Medical College of Wisconsin Milwaukee WI.
Medical College of Wisconsin · USChildren's Hospital of Wisconsin · USGeorgia State University · USFederal Almazov North-West Medical Research Centre · RU

Funding

AMP-Activated Protein Kinase in DiabetesR01HL080499 · NHLBI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ZOU, MING-HUI · 2006 to 2019
$5.8M
SNRK in ischemic vascular diseasesR01HL142287 · NHLBI · GEORGIA STATE UNIVERSITY · PI XIE, ZHONGLIN, ZOU, MING-HUI · 2018 to 2022
$3.0M
Liver kinase B1 in angiogenesisR01CA213022 · NCI · GEORGIA STATE UNIVERSITY · PI ZOU, MING-HUI · 2017 to 2021
$2.3M
Delta like-4 long non-coding RNA function in angiogenesis and vascular anomaliesR01HL123338 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2015 to 2018
$1.8M
Developing nicorandil and companion biomarkers for DMD cardiomyopathy therapyR01HL134932 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI LAWLOR, MICHAEL WILLIAM · 2017 to 2020
$1.8M
R13 Vasculata Conference 2019R13HL147501 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2019 to 2019
$20k
NCI NIH HHS R01 CA213022NHLBI NIH HHS R01 HL080499NHLBI NIH HHS R01 HL123338NHLBI NIH HHS R01 HL134932NHLBI NIH HHS R01 HL142287NHLBI NIH HHS R13 HL147501
6 · The paper itself

Abstract

Background The SNRK (sucrose-nonfermenting-related kinase) enzyme is critical for cardiac function. However, the underlying cause for heart failure observed in

Indexed as

Angiotensin IIAnimalsCell LineEndothelial CellsFibrosisHeartHeart FailureInflammationIn Vitro TechniquesMacrophagesMiceMice, KnockoutMyocardiumMyocytes, CardiacNF-kappa BProtein Serine-Threonine KinasesAngiotensin IINF-kappa BProtein Serine-Threonine KinasesSnrk protein, mouseVasoconstrictor Agentscardiac hypertrophycardiomyocyteendothelial cellfibrosisheart failureinflammationNF‐kB

Identifiers

PMID31718444
PMCPMC6915262
OpenAlexW2988618388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.