Evidence map›Paper›PMID 31718063›Full record

ReviewInternational journal of molecular sciences2019

Cytonemes, Their Formation, Regulation, and Roles in Signaling and Communication in Tumorigenesis.

Sergio Casas-Tintó, Marta Portela

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  8. Intercellular Highways in Transport Processes.Results and problems in cell differentiation · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Circadian GeneInternational journal of molecular sciences · 2022
    Article
  14. Article
  15. JNK Pathway in CNS Pathologies.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Basic and Translational Models of Cooperative Oncogenesis.International journal of molecular sciences · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Sergio Casas-TintóInstituto Cajal-CSIC. Av. del Doctor Arce, 37. 28002 Madrid, Spain.
Marta PortelaDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Instituto Cajal · ESLa Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence during the past two decades shows that cells interconnect and communicate through cytonemes. These cytoskeleton-driven extensions of specialized membrane territories are involved in cell-cell signaling in development, patterning, and differentiation, but also in the maintenance of adult tissue homeostasis, tissue regeneration, and cancer. Brain tumor cells in glioblastoma extend ultralong membrane protrusions (named tumor microtubes, TMs), which contribute to invasion, proliferation, radioresistance, and tumor progression. Here we review the mechanisms underlying cytoneme formation, regulation, and their roles in cell signaling and communication in epithelial cells and other cell types. Furthermore, we discuss the recent discovery of glial cytonemes in the

Indexed as

Cell CommunicationActin CytoskeletonAnimalsCarcinogenesisCell Surface ExtensionsDrosophilaEpithelial CellsSignal TransductionCytonemesDppDrosophilaEGFepithelial cellsFGFglioblastomaHhtumourgenesisWg

Identifiers

PMID31718063
PMCPMC6888727
OpenAlexW2985152838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.