Evidence map›Paper›PMID 31718036›Full record

ArticleMicroorganisms2019

Computational Modelling of Metabolic Burden and Substrate Toxicity in

Martin Demko, Lukáš Chrást, Pavel Dvořák, Jiří Damborský, David Šafránek

Abstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Construction of a syntrophicSynthetic biology (Oxford, England) · 2025
    Article
  4. Enhancing the antibacterial function of probioticApplied and environmental microbiology · 2023
    Article
  5. Biodegradation of aromatic pollutants meets synthetic biology.Synthetic and systems biotechnology · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin DemkoSystems Biology Laboratory, Faculty of Informatics, Masaryk University, Botanická 68a, 602 00 Brno, Czech Republic.
Lukáš ChrástLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5, Bld. A13, 625 00 Brno, Czech Republic.
Pavel DvořákDepartment of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, Bld. A25, 625 00 Brno, Czech Republic.
Jiří DamborskýLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5, Bld. A13, 625 00 Brno, Czech Republic.ORCID 0000-0002-7848-8216
David ŠafránekSystems Biology Laboratory, Faculty of Informatics, Masaryk University, Botanická 68a, 602 00 Brno, Czech Republic.

Funding

Czech Ministry of Education CZ.02.1.01/0.0/0.0/1_026/0008451Czech Ministry of Education CZ.02.1.01/0.0/0.0/16_019/000086Czech Ministry of Education LM2015047Czech Ministry of Education LM2015055Grant Agency of Czech Republic GA18-00178SHorizon 2020 Framework Programme 720776Seventh Framework Programme 722610
6 · The paper itself

Abstract

In our previous work, we designed and implemented a synthetic metabolic pathway for 1,2,3-trichloropropane (TCP) biodegradation in

Indexed as

biodegradationcomputational modellingenvironmental pollutantsmetabolic burdenpopulation growth

Identifiers

PMID31718036
PMCPMC6921056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.