ArticlePolymers2019
Flat Die Extruded Biocompatible Poly(Lactic Acid) (PLA)/Poly(Butylene Succinate) (PBS) Based Films.
Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Universal Method for Covalent Attachment of Hydrogels to Diverse Polymeric Surfaces for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Changes in the Thermal and Structural Properties of Polylactide and Its Composites During a Long-Term Degradation Process.Polymers · 2025Article
- Application of Poly(lactic Acid) Composites in the Automotive Sector: A Critical Review.Polymers · 2024Review
- Petal-like Patterning of Polylactide/Poly (Butylene Succinate) Thin Films Induced by Phase Separation.Polymers · 2023Article
- Rosmarinic and Glycyrrhetinic Acid-Modified Layered Double Hydroxides as Functional Additives for Poly(Lactic Acid)/Poly(Butylene Succinate) Blends.Molecules (Basel, Switzerland) · 2023Article
- Effect of Nanocellulose Types on Microporous Acrylic Acid/Sodium Alginate Super Absorbent Polymers.Journal of functional biomaterials · 2022Article
- Improvement of Interfacial Adhesion and Thermomechanical Properties of PLA Based Composites with Wheat/Rice Bran.Polymers · 2022Article
- Review
- Liquid and Solid Functional Bio-Based Coatings.Polymers · 2021Review
- Effect of Mineral Fillers on the Mechanical Properties of Commercially Available Biodegradable Polymers.Polymers · 2021Article
- Article
- Biobased Materials for Skin-Contact Products Promoted by POLYBIOSKIN Project.Journal of functional biomaterials · 2020Article
- Properties of Biodegradable Films Based on Poly(butylene Succinate) (PBS) and Poly(butylene Adipate-Polymers · 2020Article
- Preparation and Compatibilization of PBS/Whey Protein Isolate Based Blends.Molecules (Basel, Switzerland) · 2020Article
- Sustainable Micro and Nano Additives for Controlling the Migration of a Biobased Plasticizer from PLA-Based Flexible Films.Polymers · 2020Article
- Modification of PLA-Based Films by Grafting or Coating.Journal of functional biomaterials · 2020Article
- Skin-Compatible Biobased Beauty Masks Prepared by Extrusion.Journal of functional biomaterials · 2020Article
- Properties and Skin Compatibility of Films Based on Poly(Lactic Acid) (PLA) Bionanocomposites Incorporating Chitin Nanofibrils (CN).Journal of functional biomaterials · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Biodegradable polymers are promising materials for films and sheets used in many widely diffused applications like packaging, personal care products and sanitary products, where the synergy of high biocompatibility and reduced environmental impact can be particularly significant. Plasticized poly(lactic acid) (PLA)/poly(butylene succinate) (PBS) blend-based films, showing high cytocompatibility and improved flexibility than pure PLA, were prepared by laboratory extrusion and their processability was controlled by the use of a few percent of a commercial melt strength enhancer, based on acrylic copolymers and micro-calcium carbonate. The melt strength enhancer was also found effective in reducing the crystallinity of the films. The process was upscaled by producing flat die extruded films in which elongation at break and tear resistance were improved than pure PLA. The in vitro biocompatibility, investigated through the contact of flat die extruded films with cells, namely, keratinocytes and mesenchymal stromal cells, resulted improved with respect to low density polyethylene (LDPE). Moreover, the PLA-based materials were able to affect immunomodulatory behavior of cells and showed a slight indirect anti-microbial effect. These properties could be exploited in several applications, where the contact with skin and body is relevant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.