Evidence map›Paper›PMID 31717851›Full record

ReviewAnimals : an open access journal from MDPI2019

Cellular Composition and Differentiation Signaling in Chicken Small Intestinal Epithelium.

Haihan Zhang, Dongfeng Li, Lingbin Liu, Ling Xu, Mo Zhu, Xi He, Yang Liu

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  7. Animals : an open access journal from MDPI · 2024
    Article
  8. Utilizing the apical-out enteroidsFrontiers in physiology · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Haihan ZhangDepartment of Animal Sciences, Hunan Agricultural University, Changsha 410128, Hunan, China.
Dongfeng LiDepartment of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, China.
Lingbin LiuCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.ORCID 0000-0001-9266-9868
Ling XuDepartment of Animal Sciences, Hunan Agricultural University, Changsha 410128, Hunan, China.
Mo ZhuDepartment of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, China.
Xi HeDepartment of Animal Sciences, Hunan Agricultural University, Changsha 410128, Hunan, China.
Yang LiuDepartment of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CNHunan Agricultural University · CNSouthwest University · CN

Funding

China Scholarship Funds 201706855037Fundamental Research Funds for the Central Universities KJQN201830National Natural Science Foundation of China 31702110
6 · The paper itself

Abstract

The small intestine plays an important role for animals to digest and absorb nutrients. The epithelial lining of the intestine develops from the embryonic endoderm of the embryo. The mature intestinal epithelium is composed of different types of functional epithelial cells that are derived from stem cells, which are located in the crypts. Chickens have been widely used as an animal model for researching vertebrate embryonic development. However, little is known about the molecular basis of development and differentiation within the chicken small intestinal epithelium. This review introduces processes of development and growth in the chicken gut, and compares the cellular characteristics and signaling pathways between chicken and mammals, including Notch and Wnt signaling that control the differentiation in the small intestinal epithelium. There is evidence that the chicken intestinal epithelium has a distinct cellular architecture and proliferation zone compared to mammals. The establishment of an in vitro cell culture model for chickens will provide a novel tool to explore molecular regulation of the chicken intestinal development and differentiation.

Indexed as

chickendifferentiationepitheliumsmall intestine

Identifiers

PMID31717851
PMCPMC6912625
OpenAlexW2981550599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.