Evidence map›Paper›PMID 31717789›Full record

ArticleGenes2019

Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine.

Hua Gong, Huitong Zhou, Jiqing Wang, Shaobin Li, Yuzhu Luo, Jonathan G H Hickford

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Association ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Review
  5. Characterisation of the OvineAnimals : an open access journal from MDPI · 2025
    Article
  6. Article
  7. Article
  8. Effects ofGenes · 2024
    Article
  9. Exploring Variation in OvineAnimals : an open access journal from MDPI · 2024
    Article
  10. Melatonin's effect on hair follicles in a goat (Frontiers in endocrinology · 2024
    Article
  11. OvineGenes · 2023
    Article
  12. Sequence Variation in CaprineAnimals : an open access journal from MDPI · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Ovine Toll-like Receptor 9 (Animals : an open access journal from MDPI · 2021
    Article
  17. The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Hua GongInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.
Huitong ZhouInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.
Jiqing WangInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0002-9811-0085
Shaobin LiInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0002-6688-1117
Yuzhu LuoInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0003-2587-5826
Jonathan G H HickfordInternational Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China.
Gansu Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The keratin-associated proteins (KAPs) are structural components of hair/wool fibres. All of the KAPs identified to date contain cysteine, which is thought to form disulphide bonds cross-linking the keratin intermediate filaments. Here, we report the identification of a KAP gene in sheep that would produce a protein that contains a high proportion (63.2 mol%) of glycine and tyrosine, but would not contain any cysteine. This suggests that other forms of intra- and inter-strand interaction may occur with this KAP, such as interactions via ring-stacking and hydrogen-bonding. The gene was dissimilar to any previously reported KAP gene, and was therefore assigned to a new family, and named

Indexed as

Polymorphism, Single NucleotideAmino Acid SubstitutionAnimalsCysteineFemaleGlycineHydrogen BondingKeratinsProtein DomainsSheepTyrosineWoolWool FiberCysteineGlycineKeratinsTyrosineKeratin-associated protein KAP36-1 gene (KRTAP36-1)prickle factorsheepvariationwool traits

Identifiers

PMID31717789
PMCPMC6896175
OpenAlexW2981413967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.