Evidence map›Paper›PMID 31717769›Full record

ReviewInternational journal of molecular sciences2019

The Functions and Therapeutic Potential of Heat Shock Proteins in Inflammatory Bowel Disease-An Update.

Abdullah Hoter, Hassan Y Naim

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  8. TheFoods (Basel, Switzerland) · 2023
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  15. Frontiers in pharmacology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Abdullah HoterDepartment of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Hassan Y NaimDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0003-4884-8425
Cairo University · EGUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Deutsche Forschungsgemeinschaft Open Access PublishingDeutscher Akademischer Austauschdienst Scholarship to A.H.Stiftung Tierärztliche Hochschule Hannover Intramural Funding and Open Access Publishing
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a multifactorial human intestinal disease that arises from numerous, yet incompletely defined, factors. Two main forms, Crohn's disease (CD) and ulcerative colitis (UC), lead to a chronic pathological form. Heat shock proteins (HSPs) are stress-responsive molecules involved in various pathophysiological processes. Several lines of evidence link the expression of HSPs to the development and prognosis of IBD. HSP90, HSP70 and HSP60 have been reported to contribute to IBD in different aspects. Moreover, induction and/or targeted inhibition of specific HSPs have been suggested to ameliorate the disease consequences. In the present review, we shed the light on the role of HSPs in IBD and their targeting to prevent further disease progression.

Indexed as

Chaperonin 60Colitis, UlcerativeCrohn DiseaseDisease ProgressionHeat-Shock ProteinsHeat-Shock Proteins, SmallHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsHumansIntestinal NeoplasmsIntestine, LargeMitochondrial ProteinsPrognosisChaperonin 60Heat-Shock ProteinsHeat-Shock Proteins, SmallHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsHSPD1 protein, humanMitochondrial ProteinschaperonesCrohn’s diseaseheat shock proteinsinflammatory bowel diseasetherapeutic functionulcerative colitis

Identifiers

PMID31717769
PMCPMC6862201
OpenAlexW2982161215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.