Evidence map›Paper›PMID 31717717›Full record

ArticleJournal of clinical medicine2019

The Predictive Accuracy of the General Movement Assessment for Cerebral Palsy: A Prospective, Observational Study of High-Risk Infants in a Clinical Follow-Up Setting.

Ragnhild Støen, Lynn Boswell, Raye-Ann de Regnier, Toril Fjørtoft, Deborah Gaebler-Spira, Espen Ihlen, Cathrine Labori, Marianne Loennecken, Michael Msall, Unn Inger Möinichen and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 49 citations in OpenAlex.

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  3. Standardizing early cerebral palsy detection in high-risk infants: reducing age at diagnosis through a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 2 countries.

Ragnhild StøenDepartment of Neonatology, St. Olavs hospital, Trondheim University Hospital, 7006 Trondheim, Norway.
Lynn BoswellAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Raye-Ann de RegnierAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.ORCID 0000-0002-2435-8571
Toril FjørtoftDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.ORCID 0000-0002-9022-3050
Deborah Gaebler-SpiraFeinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-6827-4241
Espen IhlenDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Cathrine LaboriDepartment of Clinical Therapeutic Services, University Hospital of North Norway, 9038 Tromsø, Norway.
Marianne LoenneckenDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Michael MsallUniversity of Chicago Medicine, Comer Children's Hospital, Section of Developmental and Behavioral Pediatrics, Chicago, IL 60637, USA.
Unn Inger MöinichenDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Colleen PeytonFeinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0003-4753-7246
Annamarie RussowAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Michael D SchreiberUniversity of Chicago Medicine, Comer Children's Hospital, Department of Pediatrics, Chicago, IL 60637, USA.
Inger Elisabeth SilbergDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Nils Thomas SongstadDepartment of Pediatrics and Adolescent Medicine, University Hospital of North Norway, 9038 Tromsø, Norway.
Randi VågenClinic of Clinical Services, St. Olavs hospital, Trondheim University Hospital, 7006 Trondheim, Norway.
Gunn Kristin ØbergDepartment of Clinical Therapeutic Services, University Hospital of North Norway, 9038 Tromsø, Norway.
Lars AddeDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Norwegian University of Science and Technology · NONorthwestern University · USOslo University Hospital · NOUniversity Hospital of North Norway · NOLurie Children's Hospital · USComer Children's Hospital · USSt Olav's University Hospital · NOUniversity of Chicago · US

Funding

The Liaison Committee between the Central Norway Regional Health Authority and the Norwegian University of Science and Technology, Trondheim, Norway SO: 90056100
6 · The paper itself

Abstract

backgroundEarly prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during the fidgety movements (FM) period has been recommended as standard of care in high-risk infants. The aim of this study was to determine the accuracy of GMA, alone or in combination with neonatal imaging, in predicting cerebral palsy (CP).

methodsInfants with increased risk of perinatal brain injury were prospectively enrolled from 2009-2014 in this multi-center, observational study. FM were classified by two certified GMA observers blinded to the clinical history. Abnormal GMA was defined as absent or sporadic FM. CP-status was determined by clinicians unaware of GMA results.

resultsOf 450 infants enrolled, 405 had scorable video and follow-up data until at least 18-24 months. CP was confirmed in 42 (10.4%) children at mean age 3 years 1 month. Sensitivity, specificity, positive and negative predictive values, and accuracy of absent/sporadic FM for CP were 76.2, 82.4, 33.3, 96.8, and 81.7%, respectively. Only three (8.1%) of 37 infants with sporadic FM developed CP. The highest accuracy (95.3%) was achieved by a combination of absent FM and abnormal neonatal imaging.

conclusionIn infants with a broad range of neonatal risk factors, accuracy of early CP prediction was lower for GMA than previously reported but increased when combined with neonatal imaging. Sporadic FM did not predict CP in this study.

Indexed as

cerebral palsyearly brain damagefidgety movementsgeneral movement assessmentneuroimaging

Identifiers

PMID31717717
PMCPMC6912231
OpenAlexW2981559833

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.