Evidence map›Paper›PMID 31717698›Full record

ReviewInternational journal of molecular sciences2019

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers.

Fabio S M Yamaguchi, Shahin Shams, Eduardo A Silva, Roberta S Stilhano

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
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  12. Review
  13. Article
  14. Bone Marrow Aspirate Matrix: A Convenient Ally in Regenerative Medicine.International journal of molecular sciences · 2021
    Review
  15. Platelet-rich plasmaWorld journal of stem cells · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabio S M YamaguchiInstitute of Orthopedics and Traumatology, School of Medicine, University of São Paulo (USP), São Paulo 05403-010, Brazil.
Shahin ShamsDepartment of Biomedical Engineering, University of California, Davis, CA 95616, USA.
Eduardo A SilvaDepartment of Biomedical Engineering, University of California, Davis, CA 95616, USA.
Roberta S StilhanoDepartment of Physiological Sciences, Santa Casa de São Paulo School of Medical Sciences (FCMSCSP), São Paulo 01221-020, Brazil.ORCID 0000-0002-0653-5968

Funding

Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
Fundação de Amparo à Pesquisa da Santa Casa de São Paulo FAP 2019/2021NIGMS NIH HHS T32 GM099608
6 · The paper itself

Abstract

Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.

Indexed as

Biocompatible MaterialsBone Marrow CellsClinical Trials as TopicHumansPlatelet-Rich PlasmaRegenerative MedicineBiocompatible Materialsbiomaterialsbonebone marrow aspirate concentrate (BMAC)cartilagemusclePlatelet Rich Plasma (PRP)

Identifiers

PMID31717698
PMCPMC6862231

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.