Evidence map›Paper›PMID 31717665›Full record

ArticleInternational journal of molecular sciences2019

Transcription Factor Prospero Homeobox 1 (PROX1) as a Potential Angiogenic Regulator of Follicular Thyroid Cancer Dissemination.

Magdalena Rudzińska, Michał Mikula, Katarzyna D Arczewska, Ewa Gajda, Stanisława Sabalińska, Tomasz Stępień, Jerzy Ostrowski, Barbara Czarnocka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Extracellular Vesicles as Signal Carriers in Malignant Thyroid Tumors?International journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Long Non-CodingNon-coding RNA · 2021
    Article
  12. Article
  13. Article
  14. Cell and Molecular Biology of Thyroid Disorders 2.0.International journal of molecular sciences · 2021
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Magdalena RudzińskaCentre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, 01-813 Warsaw, Poland.
Michał MikulaMaria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Genetics, 02-781 Warsaw, Poland.
Katarzyna D ArczewskaCentre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, 01-813 Warsaw, Poland.ORCID 0000-0001-9606-1585
Ewa GajdaCentre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, 01-813 Warsaw, Poland.ORCID 0000-0002-3774-3989
Stanisława SabalińskaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 02-109 Warsaw, Poland.
Tomasz StępieńClinic of Endocrinological and General Surgery, Medical University of Łódź, 91-513 Łódź, Poland.
Jerzy OstrowskiMaria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Genetics, 02-781 Warsaw, Poland.
Barbara CzarnockaCentre of Postgraduate Medical Education, Department of Biochemistry and Molecular Biology, 01-813 Warsaw, Poland.ORCID 0000-0001-7701-760X
Postgraduate School of Molecular Medicine · PLInstitute of Biocybernetics and Biomedical Engineering · PLMedical University of Lodz · PLSechenov University · RUThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

Narodowe Centrum Nauki 2012/07/B/ NZ5/02444Narodowe Centrum Nauki 2013/11/N/NZ5/03394
6 · The paper itself

Abstract

It is well known that Prospero homeobox 1 (PROX1) is a crucial regulator of lymphangiogenesis, that reprograms blood endothelial cells to lymphatic phenotype. However, the role of PROX1 in tumor progression, especially in angiogenesis remains controversial. Herein, we studied the role of PROX1 in angiogenesis in cell lines derived from follicular thyroid cancer (FTC: FTC-133) and squamous cell carcinoma of the thyroid gland (SCT: CGTH-W-1) upon

Indexed as

Gene Expression Regulation, NeoplasticAdenocarcinoma, FollicularCarcinoma, Squamous CellCells, CulturedEndothelial Growth FactorsHomeodomain ProteinsHumansNeovascularization, PathologicProspero-Related Homeobox 1 ProteinThyroid GlandThyroid NeoplasmsTumor Suppressor ProteinsEndothelial Growth FactorsHomeodomain ProteinsProspero-Related Homeobox 1 ProteinTumor Suppressor Proteinsangiogenesisfollicular thyroid cancerPROX1

Identifiers

PMID31717665
PMCPMC6888435
OpenAlexW2986607651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.