ArticleMolecules (Basel, Switzerland)2019
Organocatalytic Asymmetric Conjugate Addition of Aldehydes to Maleimides and Nitroalkenes in Deep Eutectic Solvents.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Nickel-Imidazolium Low Transition Temperature Mixtures with Lewis-Acidic Character.Molecules (Basel, Switzerland) · 2023Article
- Asymmetric Conjugate Addition of Ketones to Maleimides Organocatalyzed by a Chiral Primary Amine-Salicylamide.Molecules (Basel, Switzerland) · 2022Article
- Deep Eutectic Solvents in Solar Energy Technologies.Molecules (Basel, Switzerland) · 2022Review
- Special Issue: Development of Asymmetric Synthesis.Molecules (Basel, Switzerland) · 2020Article
- Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds.Molecules (Basel, Switzerland) · 2020Article
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Authors and funding
4 authors.
Funding
Abstract
A chiral primary amine-salicylamide is used as an organocatalyst for the enantioselective conjugate addition of α,α-disubstituted aldehydes to maleimides and nitroalkenes. The reactions are performed in deep eutectic solvents as reaction media at room temperature, leading to the corresponding adducts with enantioselectivities up to 88% (for maleimides) and 80% (for nitroalkenes). Catalyst and solvent can be recovered and reused.
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Registered trials
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