ReviewNutrients2019
Plant-Based Diets in the Reduction of Body Fat: Physiological Effects and Biochemical Insights.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 5 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Mediterranean diet versus low-fat diet on cardiovascular disease (CVD) risk factors and outcomes: A systematic review of RCTs.Medicine · 2026Pooled it
- Reducing meat and/or dairy consumption in adults: a systematic review and meta-analysis of effects on protein intake, anthropometric values, and body composition.Nutrition reviews · 2024Pooled it
- The effects of vegetarian diets on glycemia and lipid parameters in adult patients with overweight and obesity: a systematic review and meta-analysis.European journal of clinical nutrition · 2023Pooled it
- The effects of consuming a Mediterranean style diet on associated COVID-19 severity biomarkers in obese/overweight adults: A systematic review.Nutrition and health · 2022Pooled it
- The Association of Plant-Based Diet With Cardiovascular Disease and Mortality: A Meta-Analysis and Systematic Review of Prospect Cohort Studies.Frontiers in cardiovascular medicine · 2021Pooled it
- Associations among pork intake, weight-loss, and diet quality outcomes in a commercial weight-management program.Nutrition & diabetes · 2026Trial
- Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis.European journal of nutrition · 2022Trial
- A Vegan Diet Is Associated with a Significant Reduction in Dietary Acid Load: Post Hoc Analysis of a Randomized Controlled Trial in Healthy Individuals.International journal of environmental research and public health · 2021Trial
- Sustainable Plant-Based Diets in Children and Adolescents: Current Evidence on Metabolic Syndrome and Cardiometabolic Health.Current nutrition reports · 2026Review
- Urinary metabolomic profiling to identify the impact of the increased intake of whole grains, vegetables, and fruits in healthy adolescents.European journal of clinical nutrition · 2026Article
- Effects of Non-Soy Legumes on Body Weight and Body Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Food science & nutrition · 2026Review
- Western Diet Induces Changes in Gene Expression in Multiple Tissues During Early Insulin Resistance and Glucose Intolerance in Male C57BL/6 Mice.Current issues in molecular biology · 2025Article
- The effect of cumulative exposure to unhealthy behavioral lifestyles on incident primary dyslipidemia: a prospective study from the Chinese government employee cohort.Lipids in health and disease · 2025Article
- Effect of Plant-Based Diets on Energy Metabolism and Metabolic Functions.Current nutrition reports · 2025Review
- Article
- Association of Air Pollution With Adiposity Rates in Active Runners and Inactive People.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- The Role of Plant-Based Nutrition and Exercise in Metabolic Syndrome: A Narrative Review.Nutrients · 2025Review
- Plant-based dietary indices association with appetite, appetite regulating peptides and gut microbiota in healthy women: a cross-sectional study.European journal of nutrition · 2025Article
- Plant-Based vs. Animal-Based Diets: Appetitive Traits and Dietary Patterns in Adults Based on Cross-Sectional Surveys.Nutrients · 2025Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity affects over one-third of Americans and increases the risk of cardiovascular disease and type II diabetes. Interventional trials have consistently demonstrated that consumption of plant-based diets reduces body fat in overweight and obese subjects, even when controlling for energy intake. Nonetheless, the mechanisms underlying this effect have not been well-defined. This review discusses six major dietary mechanisms that may lead to reduced body fat. These include (1) reduced caloric density, (2) improved gut microbiota symbiosis, (3) increased insulin sensitivity, (4) reduced trimethylamine-N-oxide (TMAO), (5) activation of peroxisome proliferator-activated receptors (PPARs), and (6) over-expression of mitochondrial uncoupling proteins. Collectively, these factors improve satiety and increase energy expenditure leading to reduced body weight.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.