Evidence map›Paper›PMID 31717445›Full record

ArticleMaterials (Basel, Switzerland)2019

In Vitro Evaluation of the Biological Effects of ACTIVA Kids BioACTIVE Restorative, Ionolux, and Riva Light Cure on Human Dental Pulp Stem Cells.

Sergio López-García, María P Pecci-Lloret, Miguel R Pecci-Lloret, Ricardo E Oñate-Sánchez, David García-Bernal, Pablo Castelo-Baz, Francisco Javier Rodríguez-Lozano, Julia Guerrero-Gironés

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. AnInternational journal of clinical pediatric dentistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sergio López-GarcíaLaboratory of Cellular Therapy and Hematopoietic Transplant, Internal Medicine Department, IMIB-Virgen de la Arrixaca, University of Murcia, Avenida Buenavista s/n, 30120 Murcia, Spain.
María P Pecci-LloretDepartament of Special Care and Gerodontology, Faculty of Medicine, University of Murcia, 30007 Murcia, Spain.
Miguel R Pecci-LloretDepartament of Special Care and Gerodontology, Faculty of Medicine, University of Murcia, 30007 Murcia, Spain.
Ricardo E Oñate-SánchezDepartament of Special Care and Gerodontology, Faculty of Medicine, University of Murcia, 30007 Murcia, Spain.
David García-BernalLaboratory of Cellular Therapy and Hematopoietic Transplant, Internal Medicine Department, IMIB-Virgen de la Arrixaca, University of Murcia, Avenida Buenavista s/n, 30120 Murcia, Spain.ORCID 0000-0001-6610-8442
Pablo Castelo-BazEndodontics Unit, Faculty of Medicine and Odontology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-3031-5532
Francisco Javier Rodríguez-LozanoLaboratory of Cellular Therapy and Hematopoietic Transplant, Internal Medicine Department, IMIB-Virgen de la Arrixaca, University of Murcia, Avenida Buenavista s/n, 30120 Murcia, Spain.ORCID 0000-0002-0623-740X
Julia Guerrero-GironésDepartament of Special Care and Gerodontology, Faculty of Medicine, University of Murcia, 30007 Murcia, Spain.

Funding

Instituto de Salud Carlos III RD16/0011/0001
6 · The paper itself

Abstract

This study aimed to analyze the biological effects of three new bioactive materials on cell survival, migration, morphology, and attachment in vitro. ACTIVA Kids BioACTIVE Restorative (Pulpdent, Watertown, MA, USA) (Activa), Ionolux (Voco, Cuxhaven, Germany), and Riva Light Cure UV (SDI, Bayswater, Australia) (Riva) were handled and conditioned with a serum-free culture medium. Stem cells from human dental pulp (hDPSCs) were exposed to material extracts, and metabolic activity, cell migration, and cell morphology were evaluated. Cell adhesion to the different materials was analyzed by scanning electron microscopy (SEM). The chemical composition of the materials was evaluated by energy-dispersive X-ray (EDX). One-way analysis of variance followed by a Tukey test was performed (

Indexed as

bioactive materialsbiological propertiescytotoxicitydental materialsdental pulp cells

Identifiers

PMID31717445
PMCPMC6888068

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.