Evidence map›Paper›PMID 31717420›Full record

ArticleBiomolecules2019

Predicting Angiogenesis by Endothelial Progenitor Cells Relying on In-Vitro Function Assays and VEGFR-2 Expression Levels.

Nadin Sabbah, Tal Tamari, Rina Elimelech, Ofri Doppelt, Utai Rudich, Hadar Zigdon-Giladi

Abstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadin SabbahLaboratory for Bone Repair, Rambam Health Care Campus, Haifa 3109600, Israel.
Tal TamariLaboratory for Bone Repair, Rambam Health Care Campus, Haifa 3109600, Israel.
Rina ElimelechLaboratory for Bone Repair, Rambam Health Care Campus, Haifa 3109600, Israel.
Ofri DoppeltLaboratory for Bone Repair, Rambam Health Care Campus, Haifa 3109600, Israel.
Utai RudichThe Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3109601, Israel.
Hadar Zigdon-GiladiLaboratory for Bone Repair, Rambam Health Care Campus, Haifa 3109600, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical trials have demonstrated the safety and efficacy of autologous endothelial progenitor cell (EPC) therapy in various diseases. Since EPCs' functions are influenced by genetic, systemic and environmental factors, the therapeutic potential of each individual EPCs is unknown and may affect treatment outcome. Therefore, our aim was to compare EPCs function among healthy donors in order to predict blood vessel formation (angiogenesis) before autologous EPC transplantation. Human EPCs were isolated from the blood of ten volunteers. EPCs proliferation rate, chemoattractant ability, and CXCR4 mRNA levels were different among donors (

Indexed as

AnimalsBlood VesselsCell MovementCell ProliferationChemotactic FactorsEndothelial Progenitor CellsGene Expression Regulation, DevelopmentalHumansMiceNeovascularization, PathologicNeovascularization, PhysiologicRNA, MessengerStem Cell TransplantationVascular Endothelial Growth Factor Receptor-2Chemotactic FactorsRNA, MessengerVascular Endothelial Growth Factor Receptor-2angiogenesischemoattractantconditioned mediumhuman endothelial progenitor cellsmesenchymal stem cellspotency assayvascular endothelial growth factor receptor 2 (VEGFR-2)

Identifiers

PMID31717420
PMCPMC6921061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.