Evidence map›Paper›PMID 31717404›Full record

ArticleInternational journal of molecular sciences2019

In Silico Study of Rett Syndrome Treatment-Related Genes,

Muhamad Fahmi, Gen Yasui, Kaito Seki, Syouichi Katayama, Takako Kaneko-Kawano, Tetsuya Inazu, Yukihiko Kubota, Masahiro Ito

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Macromolecular Interactions of Disordered Proteins.International journal of molecular sciences · 2020
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhamad FahmiAdvanced Life Sciences Program, Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.ORCID 0000-0003-4359-1405
Gen YasuiAdvanced Life Sciences Program, Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Kaito SekiAdvanced Life Sciences Program, Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Syouichi KatayamaDepartment of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Takako Kaneko-KawanoDepartment of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Tetsuya InazuDepartment of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Yukihiko KubotaDepartment of Bioinformatics, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.ORCID 0000-0002-8151-9888
Masahiro ItoAdvanced Life Sciences Program, Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.

Funding

MEXT-supported program for the strategic research foundation at private universities 2015-2019
6 · The paper itself

Abstract

Rett syndrome (RTT), a neurodevelopmental disorder, is mainly caused by mutations in methyl CpG-binding protein 2 (

Indexed as

Computer SimulationEvolution, MolecularAnimalsChordataForkhead Transcription FactorsGene OntologyHumansMethyl-CpG-Binding Protein 2Mutation, MissenseNerve Tissue ProteinsOrgan SpecificityPhylogenyProtein BindingProtein Processing, Post-TranslationalProtein Serine-Threonine KinasesRett SyndromeCDKL5 protein, humanForkhead Transcription FactorsFOXG1 protein, humanMethyl-CpG-Binding Protein 2Nerve Tissue ProteinsProtein Serine-Threonine Kinasescyclin-dependent kinase-like 5forkhead box protein G1intrinsically disordered regionmethyl-CpG-binding protein 2phylogenetic profile analysispost-transcriptional modificationRett syndrome

Identifiers

PMID31717404
PMCPMC6888432

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.