Evidence map›Paper›PMID 31717368›Full record

ArticleNutrients2019

Potato-Resistant Starch Supplementation Improves Microbiota Dysbiosis, Inflammation, and Gut-Brain Signaling in High Fat-Fed Rats.

Elizabeth A Klingbeil, Carolina Cawthon, Rebecca Kirkland, Claire B de La Serre

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Nutrient-Based Appetite Regulation.Journal of obesity & metabolic syndrome · 2022
    Review
  17. Article
  18. Article
  19. Effects of Heat Stress on Gut Microbiome in Rats.Indian journal of microbiology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elizabeth A KlingbeilDepartment of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA.
Carolina CawthonDepartment of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA.
Rebecca KirklandDepartment of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA.
Claire B de La SerreDepartment of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0001-8355-6087
University of Georgia · US

Funding

Alliance for Potato Research & Education AWD00007259
6 · The paper itself

Abstract

(1) High-fat (HF) diet leads to gut microbiota dysbiosis which is associated with systemic inflammation. Bacterial-driven inflammation is sufficient to alter vagally mediated satiety and induce hyperphagia. Promoting bacterial fermentation improves gastrointestinal (GI) epithelial barrier function and reduces inflammation. Resistant starch escape digestion and can be fermented by bacteria in the distal gut. Therefore, we hypothesized that potato RS supplementation in HF-fed rats would lead to compositional changes in microbiota composition associated with improved inflammatory status and vagal signaling. (2) Male Wistar rats (

Indexed as

Dietary SupplementsDysbiosisGastrointestinal MicrobiomeSolanum tuberosumAnimal FeedAnimalsBacteriaBrainDiet, High-FatDisease Models, AnimalFeeding BehaviorFermentationHyperphagiaInflammationIntestinesMaleStarchglucose tolerancegut microbiotainflammationobesityresistant starchvagal nerve

Identifiers

PMID31717368
PMCPMC6893629
OpenAlexW2985523803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.