Evidence map›Paper›PMID 31717307›Full record

ArticleCancers2019

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma.

Tarek Kröhler, Sonja M Kessler, Kevan Hosseini, Markus List, Ahmad Barghash, Sonika Patial, Stephan Laggai, Katja Gemperlein, Johannes Haybaeck, Rolf Müller and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

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  14. The Emerging Role of Stress Granules in Hepatocellular Carcinoma.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 4 countries.

Tarek KröhlerDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.
Sonja M KesslerDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-8591-851X
Kevan HosseiniDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.
Markus ListDepartment for Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany.ORCID 0000-0002-0941-4168
Ahmad BarghashSchool of Electrical Engineering and Information Technology, German Jordanian University, Amman 11180, Jordan.
Sonika PatialThe Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Stephan LaggaiDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.
Katja GemperleinDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research, 66123 Saarbrücken, Germany.
Johannes HaybaeckDepartment of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany.
Rolf MüllerDepartment of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research, 66123 Saarbrücken, Germany.
Volkhard HelmsCenter for Bioinformatics, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-2180-9154
Marcel H SchulzDepartment for Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany.
Jessica HoppstädterDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.
Perry J BlackshearThe Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Alexandra K KiemerDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-7224-9900
Saarland University · DEHelmholtz Centre for Infection Research · DEGerman Jordanian University · JOGoethe University Frankfurt · DEInnsbruck Medical University · ATLouisiana State University · USMartin Luther University Halle-Wittenberg · DEMax Planck Institute for Informatics · DENational Institute of Environmental Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic lipid deposition and inflammation represent risk factors for hepatocellular carcinoma (HCC). The mRNA-binding protein tristetraprolin (TTP, gene name

Indexed as

BCL2chemoresistanceflow cytometryHepG2Huh7liver cancerMYCNASHNEAT1VEGFA

Identifiers

PMID31717307
PMCPMC6896064
OpenAlexW2984262233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.