ArticleCancer medicine2020
Epidemiologic trends and geographic distribution of esophageal cancer in Canada: A national population-based study.
Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- CBL with integrated SDH versus CBL alone in esophageal surgery internship: a randomized controlled trial on clinical competence development.BMC medical education · 2026Trial
- Spatial clustering of esophageal cancer in central Oromia, Ethiopia: A spatial autocorrelation and scan statistics analysis.PloS one · 2026Article
- Canadian Consensus Recommendations for Predictive Biomarker Testing in Gastric and Gastroesophageal Junction Adenocarcinoma.Current oncology (Toronto, Ont.) · 2024Review
- Outcomes from a single institution cohort of 248 patients with stage I-III esophageal cancer treated with radiotherapy: Comparison of younger and older populations.Technical innovations & patient support in radiation oncology · 2024Article
- Article
- Burden of esophageal cancer between 2010 and 2019 in Asian countries by geographical region and sociodemographic index: A comparison with global data.Thoracic cancer · 2023Article
- Investigation of the Incidence and Geographic Distribution of Bone and Soft Tissue Sarcomas in Canada: A National Population-Based Study.Current oncology (Toronto, Ont.) · 2023Article
- Bile acid sequestrants in poor healing after endoscopic therapy of Barrett's esophagus.Clinical endoscopy · 2023Article
- Overall survival analyses of female malignancies in Southern Brazil during 2008-2017: A closer look at breast, cervical and ovarian cancer.Dialogues in health · 2022Review
- The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review.International journal of molecular sciences · 2022Review
- Acceptance and disparities of PET/CT use in patients with esophageal or gastro-esophageal junction cancer: Evaluation of mature registry data.Frontiers in nuclear medicine · 2022Article
- Population-Based Study Detailing Cutaneous Melanoma Incidence and Mortality Trends in Canada.Frontiers in medicine · 2022Article
- Geographic and Socioeconomic Disparity of Gastric Cancer Patients in Canada.Current oncology (Toronto, Ont.) · 2021Article
- Incidence and Mortality of Prostate Cancer in Canada during 1992-2010.Current oncology (Toronto, Ont.) · 2021Article
- Clinico-Pathological Findings and Spatial Distributions of Esophageal Cancer in Arsi Zone, Oromia, Central Ethiopia.Cancer management and research · 2021Article
- Trends in incidence and mortality of esophageal cancer in Inner Mongolia, 2010-2015.Thoracic cancer · 2020Article
- Investigating epidemiologic trends and the geographic distribution of patients with anal squamous cell carcinoma throughout Canada.Current oncology (Toronto, Ont.) · 2020Article
- Epidemiologic trends and geographic distribution of esophageal cancer in Canada: A national population-based study.Cancer medicine · 2020Article
- Spatiotemporal Distribution, Time to Treatment Outcome Clustering and Determinants of Esophageal Cancer in Ethiopia, a Scoping Study.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophageal cancer can be subdivided into two main histological subtypes with significant variability in their etiology and epidemiology. The incidence of esophageal adenocarcinoma (AC) is increasing across the developed countries, whereas the incidence of esophageal squamous cell carcinoma (SCC) is declining. Several risk factors have been identified in the pathogenesis of each subtype, however, their epidemiologic characteristics and distribution throughout Canada remain poorly understood.
methodsWe performed a retrospective analysis of demographic data across Canada from 1992 to 2010 using two independent population-based cancer registries. The incidence of esophageal cancer, for each subtype, was examined at the levels of provinces/territories, cities, and postal codes.
resultsA total of 19 790 patients were diagnosed with esophageal cancer in Canada between 1992 and 2010; 74% were males. The average national incidence rate was 33.5 cases per million individuals per year. Incidence of esophageal AC increased over time, with notable high-incidence rates on the Vancouver Island, the coasts of the Great Lakes, and the coasts of the Northumberland Strait in the Maritimes. The overall incidence of esophageal SCC has decreased. However, high incidence of esophageal SCC was detected in the Vancouver city, rural eastern Québec, and in the Maritimes. We also report clustering for each subtype using postal codes, which sheds light onto new avenues of research for potential environmental etiologies.
conclusionsThis study, for the first time, provides a detailed analysis on the burden of esophageal cancer in Canada, revealing important geographic clustering trends.
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