Evidence map›Paper›PMID 31715377›Full record

ArticleJournal of inorganic biochemistry2020

Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.

Stephen J Beebe, Michael J Celestine, Jimmie L Bullock, Shayna Sandhaus, Jessa Faye Arca, Donald M Cropek, Tekettay A Ludvig, Sydney R Foster, Jasmine S Clark, Floyd A Beckford and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. A Comparison ofInorganica chimica acta · 2024
    Article
  4. Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Stephen J BeebeThe Frank Reidy Center for Bioelectrics, 4211 Monarch Way, Suite 300, Norfolk, VA 23529, USA.
Michael J CelestineDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Jimmie L BullockDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Shayna SandhausDepartment of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA.
Jessa Faye ArcaDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, 118 College Drive, Hattiesburg, MS 39406, USA.
Donald M CropekU.S. Army Corps of Engineers, Construction Engineering Research Laboratory, Champaign, IL 61822, USA.
Tekettay A LudvigDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Sydney R FosterDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Jasmine S ClarkDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Floyd A BeckfordThe University of Virginia's College at Wise, 1 College Avenue, Wise, VA 24293, USA.
Criszcele M TanoDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Elizabeth A Tonsel-WhiteDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Raj K GurungDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Courtney E StankavichDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA.
Yuk-Ching Tse-DinhDepartment of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA.
William L JarrettSchool of Polymers and High-Performance Materials, The University of Southern Mississippi, 118 College Drive, #5050, Hattiesburg, MS 39406, USA.
Alvin A HolderDepartment of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA. Electronic address: aholder@odu.edu.
Old Dominion University · USFlorida International University · USUniversity of Southern Mississippi · USConstruction Engineering Research LaboratoryUniversity of Virginia's College at Wise · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
TOUGALOO PROTEOMICSP20RR016476 · NCRR · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MAO, JINGHE · 2001 to 2011
$30.4M
MARC Undergraduate Student Training in Academic Research Program at Old Dominion UniversityT34GM118259 · NIGMS · OLD DOMINION UNIVERSITY · PI HOLDER, ALVIN ANDERSON · 2018 to 2022
$1.6M
NCRR NIH HHS P20 RR016476NIGMS NIH HHS P20 GM103476NIGMS NIH HHS T34 GM118259
6 · The paper itself

Abstract

In this study, 9-anthraldehyde-N(4)-methylthiosemicarbazone (MeATSC) 1 and [Co(phen)

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell Line, TumorCobaltCoordination ComplexesDNADNA Topoisomerases, Type IDNA Topoisomerases, Type IIHumansMiceOrganometallic CompoundsThiosemicarbazonesTopoisomerase InhibitorsAntineoplastic AgentsCobaltCoordination ComplexesDNADNA Topoisomerases, Type IDNA Topoisomerases, Type IIOrganometallic CompoundsThiosemicarbazonesTopoisomerase Inhibitors(59)Co NMR spectroscopyBreast cancerCalf thymus DNACobalt(III) complexMitochondrial membrane potentialThiosemicarbazone

Identifiers

PMID31715377
PMCPMC7053658
OpenAlexW2986884503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.