Evidence map›Paper›PMID 31715316›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2020

Utilizing cooled liquid chromatography and chemical derivatization to separate and quantify C3-epimers of 25-hydroxy vitamin D and low abundant 1α,25(OH)

Brian C DeFelice, Theresa L Pedersen, Hanan Shorrosh, Randi K Johnson, Jennifer A Seifert, Jill M Norris, Oliver Fiehn

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brian C DeFeliceNIH West Coast Metabolomics Center, University of California, Davis, CA, 95616, USA.
Theresa L PedersenDepartment of Food Science and Technology, University of California, Davis, CA, 95616, USA.
Hanan ShorroshDepartment of Epidemiology, Colorado School of Public Health, Aurora, CO 80045, USA.
Randi K JohnsonBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jennifer A SeifertBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jill M NorrisBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Oliver FiehnNIH West Coast Metabolomics Center, University of California, Davis, CA, 95616, USA. Electronic address: ofiehn@ucdavis.edu.
University of California, Davis · USUniversity of Colorado Anschutz Medical Campus · USColorado School of Public Health · US

Funding

West Coast Metabolomics Center for Compound IdentificationU2CES030158 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2018 to 2021
$4.1M
Nutrigenetics & -genomics of Vitamin D and Omega-3 Fatty Acids in Type 1 DiabetesR01DK104351 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI NORRIS, JILL M · 2014 to 2018
$2.9M
NIDDK NIH HHS R01 DK104351NIEHS NIH HHS U2C ES030158
6 · The paper itself

Abstract

There is need for a single assay able to quantify the most biologically active metabolite, 1α,25-dihydroxy-vitamin-D3, and the recently discovered biologically distinct C3-epimers of 25OHD, in addition to traditional vitamin D metabolites. We developed a method of chromatographic separation and absolute quantification of the following ten forms of vitamin D: 3-epi-25OHD3, 25OHD3, 3-epi-25OHD2, 25OHD2, 1α,25(OH)

Indexed as

AdolescentAdultCase-Control StudiesChildChild, PreschoolChromatography, LiquidCohort StudiesDiabetes Mellitus, Type 1FemaleHumansInfantInfant, NewbornMaleTandem Mass SpectrometryVitamin DYoung Adult25-hydroxyvitamin Ddihydroxy-vitamin D3Vitamin D1α,25-dihydroxy-vitamin-D3C3-epimersCooled-chromatographyLC-MS/MSQuantitationVitamin D

Identifiers

PMID31715316
PMCPMC7363309
OpenAlexW2989325523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.