ArticleAmerican journal of ophthalmology2020
Comparison of Short- And Long-Term Variability in Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma.
Article in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Evaluation of the long-term variability of macular OCT/OCTA and visual field parameters.The British journal of ophthalmology · 2024Observational
- Clinical Factors Associated With Long-Term OCT Variability in Glaucoma.American journal of ophthalmology · 2023Article
- Long-term reproducibility of optical coherence tomography angiography in healthy and stable glaucomatous eyes.The British journal of ophthalmology · 2023Article
- Long- and Short-Term Variability of Perimetry in Glaucoma.Translational vision science & technology · 2022Article
- RetiNerveNet: using recursive deep learning to estimate pointwise 24-2 visual field data based on retinal structure.Scientific reports · 2021Article
- Mapping the binocular scotoma in macular degeneration.Journal of vision · 2021Article
- Comparing the Rule of 5 to Trend-based Analysis for Detecting Glaucoma Progression on OCT.Ophthalmology. GlaucomaArticle
- Deep Learning-Assisted Detection of Glaucoma Progression in Spectral-Domain OCT.Ophthalmology. GlaucomaArticle
- A Bibliometric and Mapping Analysis of Glaucoma Research between 1900 and 2019.Ophthalmology. GlaucomaArticle
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Authors and funding
8 authors.
Funding
Abstract
purposeTo assess short- and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma.
designProspective cohort.
methodsOrdinary least squares linear regression of SAP mean deviation (MD) and SD-OCT global retinal nerve fiber layer (RNFL) thickness were fitted over time for sequential tests conducted within 5 weeks (short-term testing) and annually (long-term testing). Residuals were obtained by subtracting the predicted and observed values, and each patient's standard deviation (SD) of the residuals was used as a measure of variability. Wilcoxon signed-rank test was performed to test the hypothesis of equality between short- and long-term variability.
resultsA total of 43 eyes of 43 glaucoma subjects were included. Subjects had a mean 4.5 ± 0.8 SAP and OCT tests for short-term variability assessment. For long-term variability, the same number of tests were performed and results annually collected over an average of 4.0 ± 0.8 years. The average SD of the residuals was significantly higher in the long-term than in the short-term period for both tests: 1.05 ± 0.70 dB vs. 0.61 ± 0.34 dB, respectively (P < 0.001) for SAP MD and 1.95 ± 1.86 μm vs. 0.81 ± 0.56 μm, respectively (P < 0.001) for SD-OCT RNFL thickness.
conclusionsLong-term variability was higher than short-term variability on SD-OCT and SAP. Because current event-based algorithms for detection of glaucoma progression on SAP and SD-OCT have relied on short-term variability data to establish their normative databases, these algorithms may be underestimating the variability in the long-term and thus may overestimate progression over time.
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