Evidence map›Paper›PMID 31713975›Full record

ReviewThe Kaohsiung journal of medical sciences2020

Neuromuscular blockade management for intraoperative neural monitoring.

I-Cheng Lu, Sheng-Hua Wu, Che-Wei Wu

Registry-linked trialAbstract readReview
In one paragraph

Review in The Kaohsiung journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06162390 (Optimal Concentration of Remifentanil for Achieving Excellent Intubating Condition During Low-dose Neuromuscular Blocking Agent Administration for Intraoperative Neuromonitoring Using Nerve Integrity Monitoring Tube), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06162390 nacompletednot on this mapstarted 2023, after this paper: background citation

Optimal Concentration of Remifentanil for Achieving Excellent Intubating Condition During Low-dose Neuromuscular Blocking Agent Administration for Intraoperative Neuromonitoring Using Nerve Integrity Monitoring Tube

TypeinterventionalSponsorKyungpook National University Chilgok HospitalRan2023 to 2024Enrolled21ConditionsThyroidectomyArmsRemifentanil
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Clinical Use of Endotracheal Intubation Without Neuromuscular Blockade: The Current Stage of Knowledge.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Neuromuscular blockade management for intraoperative neural monitoring.The Kaohsiung journal of medical sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

I-Cheng LuDepartment of Anesthesiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0001-6643-1071
Sheng-Hua WuDepartment of Anesthesiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Che-Wei WuDepartment of Otorhinolaryngology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0003-1052-5348

Funding

Kaohsiung Medical University KMUH107-7R89Kaohsiung Municipal Siaogang Hospital Kmhk-105-019
6 · The paper itself

Abstract

This article reviews the literature on development of neuromuscular blockade management in thyroid surgery with intraoperative neural monitoring (IONM) in the past decade. Neuromuscular blockade management includes the choice of neuromuscular blocking agents (NMBAs) and reversal of neuromuscular blockade by sugammadex. A series of animal study and clinical trials showed NMBAs effect on IONM in thyroid surgery. We summarized five NMBA regimens for IONM: (a) relaxant-free regimen, (b) depolarizing NMBA-succinylcholine, (c) titration of nondepolarizing NMBA, and (d) rocuronium combined with sugammadex. The proper management of neuromuscular blockade during IONM has greatly developed over the past decade. The misuse of NMBAs is associated with false IONM interpretations to surgeons. A detailed understanding of NMBAs and neuromuscular blockade management by sugammadex may optimize IONM quality in patients receiving monitored thyroid surgery.

Indexed as

Monitoring, IntraoperativeNeuromuscular BlockadeAnimalsDose-Response Relationship, DrugHumansNeuromuscular Nondepolarizing AgentsNeuromuscular Nondepolarizing Agentsintraoperative neural monitoringneuromuscular blocking agentsrecurrent laryngeal nervethyroid surgery

Identifiers

PMID31713975
PMCPMC11896362

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.