Evidence map›Paper›PMID 31713839›Full record

ArticleEuropean journal of immunology2020

A pan-inflammatory microRNA-cluster is associated with orbital non-Hodgkin lymphoma and idiopathic orbital inflammation.

Kamil G Laban, Rachel Kalmann, Cornelis P J Bekker, Sanne Hiddingh, Rob L P van der Veen, Christine A E Eenhorst, Stijn W Genders, Maarten P Mourits, Fleurieke H Verhagen, Emmerik F A Leijten and 5 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Serum metabolic patterns reveal the diagnostic and prognostic role of alanine abnormality in ocular adnexal lymphoma.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Kamil G LabanOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-8817-371X
Rachel KalmannOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Cornelis P J BekkerLaboratory of Translational Immunology, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Sanne HiddinghOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Rob L P van der VeenDepartment of Ophthalmology, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Christine A E EenhorstDepartment of Ophthalmology, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Stijn W GendersDepartment of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.
Maarten P MouritsDepartment of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.
Fleurieke H VerhagenOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.ORCID 0000-0001-8793-4954
Emmerik F A LeijtenLaboratory of Translational Immunology, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Saskia HaitjemaLaboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Mark C H de GrootLaboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Timothy R D J RadstakeOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Joke H de BoerOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Jonas J W KuiperOphthalmo-Immunology Unit, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Utrecht University · NLAmsterdam UMC Location University of Amsterdam · NLLeiden University Medical Center · NL

Funding

Dr. F.P. Fischer-Stichting FS2016-1Rotterdamse Stichting Blindenbelangen "Een nieuwe bloedtest voor het detecteren van oogkStichting Ankie HakStichting Lijf en Leven "Een nieuwe bloedtest voor het detecteren van oo
6 · The paper itself

Abstract

Non-Hodgkin orbital lymphoma (NHOL) and idiopathic orbital inflammation (IOI) are common orbital conditions with largely unknown pathophysiology that can be difficult to diagnose. In this study we aim to identify serum miRNAs associated with NHOL and IOI. We performed OpenArray

Indexed as

AdultAgedFemaleHumansInflammationLymphoma, Non-HodgkinMaleMicroRNAsMiddle AgedOrbital DiseasesOrbital NeoplasmsMicroRNAsB cellidiopathic orbital inflammationmicroRNAneutrophilnon-hodgkin orbital lymphoma

Identifiers

PMID31713839
PMCPMC6973116
OpenAlexW2984515585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.