Evidence map›Paper›PMID 31713746›Full record

ArticleClinical oral investigations2020

Management of anticoagulated patients in dentoalveolar surgery: a clinical comparative study.

C M Schmitt, B Rusche, R Clemm, F W Neukam, M Buchbender

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04846114 (Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04846114 nacompletednot on this map

Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study

TypeinterventionalSponsorJorge Ernesto AguilarRan2016 to 2019Enrolled71ConditionsOral Anticoagulant TherapyArmsDental implant surgery
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

C M SchmittDepartment of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany. Schmitcn@outlook.de.ORCID http://orcid.org/0000-0002-9028-5139
B RuscheDepartment of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
R ClemmDepartment of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
F W NeukamDepartment of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
M BuchbenderDepartment of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis prospective, comparative, clinical study analyzed the postoperative bleeding risk of patients on anticoagulation therapy (AT) who were undergoing tooth extractions and osteotomies. MATERIALS AND

methodsPatients with the following ATs were included (test groups): (1.) platelet aggregation inhibitors (PAIs), (2.) vitamin K inhibitors, (3.) low molecular weight heparin (LMWH), and (4.) direct oral anticoagulants (DOACs). Patients in the control group were not on any AT (non-AT group). Patients were subdivided into the following treatment groups: (1.) single tooth extraction, (2.) serial extraction (≥ 2 adjacent teeth), and (3.) tooth osteotomy. Pre-, intra-, and postoperative data concerning the treatment, extent of the surgery, and bleeding were recorded and statistically evaluated.

resultsThere were 15 postoperative bleeding events in 838 patients (1.7%): four (0.7%) in the non-AT group (n = 603 patients) and 11 (4.7%) in the AT group (n = 235 patients). The surgical procedure had no statistically significant effect on postoperative bleeding frequencies. Patients taking vitamin K inhibitors had a significantly higher risk of postoperative bleeding compared with patients without AT (p < 0.00001). Four patients were hospitalized due to the severity of the bleeding (vitamin K inhibitor group). Postoperative bleeding events were all controlled with local hemostatic measures.

conclusionsThe postoperative bleeding risk after tooth extractions and osteotomies in patients continuing AT is low, and bleeding can be controlled with local hemostatic measures. CLINICAL RELEVANCE: AT should be continued in patients undergoing tooth removal procedures under the provision that local hemostatic measures are applied.

Indexed as

AnticoagulantsHeparin, Low-Molecular-WeightHumansPostoperative HemorrhageProspective StudiesTooth ExtractionVitamin KAnticoagulantsHeparin, Low-Molecular-WeightVitamin KAnticoagulation therapyOral surgeryOsteotomyTooth extraction

Identifiers

PMID31713746
OpenAlexW2984393881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.