Evidence map›Paper›PMID 31713734›Full record

ArticleClinical rheumatology2020

Comparing the association of widespread pain, multi-joint pain and low back pain with measures of pain sensitization and function in people with knee osteoarthritis.

Olivier Guérard, Samuel Dufort, Laurence Forget Besnard, Alexis Gougeon, Lisa Carlesso

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivier GuérardÉcole de réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Canada.
Samuel DufortÉcole de réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Canada.
Laurence Forget BesnardÉcole de réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Canada.
Alexis GougeonÉcole de réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Canada.
Lisa CarlessoÉcole de réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Canada. carlesl@mcmaster.ca.ORCID http://orcid.org/0000-0002-6167-897X

Funding

International Association for the Study of Pain Early Career AwardQuebec Rehabilitation Research Network Clinical programme 1.1
6 · The paper itself

Abstract

INTRODUCTION/

objectivesTo compare 1. measures of pain sensitization (PS) in people with widespread pain (WSP), multi-joint pain, low back pain (LBP) and knee osteoarthritis (KOA) only, in people with knee OA and 2. results of self-reported function and physical performance tests amongst these sub groups. METHODOLOGY: Patients with knee OA consulting an orthopaedic surgeon were recruited from three Montreal area hospitals. A body homunculus was used to identify the presence of WSP (Y/N), multi-joint pain using a joint count (≥ 2 joints) and LBP (Y/N). Tests included pressure pain thresholds (PPT), temporal summation (TS), conditioned pain modulation and three physical performance tests. The Knee Injury and Osteoarthritis Outcome Score (KOOS) assessed self-reported function. Means were compared with Welch's ANOVA, post hoc tests and multiple regression analysis were performed.

resultsTwo hundred twenty-one participants were evaluated (mean age: 63.4 ± 9.9 years, females n = 135 (61.1%)). Those with WSP significantly differed from those with LBP on PPT mean - 1.4, 95%CI (- 2.4, - 0.4), TS 10.3 (2.1, 18.5) and the stair climb test (SCT) 5.6 (1.3, 9.9). Those with WSP significantly differed from those with KOA only on TS 9.5 (1.0, 18.1), SCT 6.3 (2.0, 10.6) and KOOS - 14.2 (- 26.5, - 2.0).

conclusionIn patients with knee OA, those with WSP demonstrated greater degrees of PS compared with those with knee OA only, LBP and multi-joint pain. They also demonstrated a slower SCT compared with those with KOA only and LBP and decreased self-reported function compared with those with KOA only. These results should be confirmed in a longitudinal study.Key Points• In people with knee OA and widespread pain, measures of sensitization, self-reported function and physical performance were poorer compared with those with knee OA and LBP, knee OA and multi-joint pain or knee OA only.• Clinicians can consider these outcomes when planning management for these subgroups planning a comprehensive treatment program for this subgroup.

Indexed as

AgedArthralgiaCentral Nervous System SensitizationCross-Sectional StudiesFemaleHumansLinear ModelsLow Back PainMaleMiddle AgedOsteoarthritis, KneePain MeasurementPain ThresholdProspective StudiesSelf ReportSeverity of Illness IndexKnee osteoarthritisLow back painMulti joint painPain sensitizationWidespread pain

Identifiers

PMID31713734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.