Evidence map›Paper›PMID 31713454›Full record

ArticleFuture medicinal chemistry2019

Sphingolipid biosynthetic pathway is crucial for growth, biofilm formation and membrane integrity of

Rodrigo Rollin-Pinheiro, Victor Pereira Rochetti, Mariana Ingrid Dutra da Silva Xisto, Livia Cristina Liporagi-Lopes, Beatriz Bastos, Antonella Rella, Ashutosh Singh, Sonia Rozental, Maurizio Del Poeta, Eliana Barreto-Bergter

Open access · greenAbstract read
In one paragraph

Article in Future medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Characterization ofFrontiers in molecular biosciences · 2022
    Article
  9. Identification of Promising Antifungal Drugs againstJournal of fungi (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Mass Spectrometric Analysis of Bioactive Sphingolipids in Fungi.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  12. Miltefosine AgainstFrontiers in cellular and infection microbiology · 2021
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rodrigo Rollin-PinheiroDepartamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Victor Pereira RochettiDepartamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Mariana Ingrid Dutra da Silva XistoDepartamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Livia Cristina Liporagi-LopesDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Beatriz BastosDepartamento de Parasitologia e Biologia Celular, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Antonella RellaMolecular Genetics & Microbiology Department, Stony Brook University, NY 11794, USA.
Ashutosh SinghMolecular Genetics & Microbiology Department, Stony Brook University, NY 11794, USA.
Sonia RozentalDepartamento de Parasitologia e Biologia Celular, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Maurizio Del PoetaMolecular Genetics & Microbiology Department, Stony Brook University, NY 11794, USA.
Eliana Barreto-BergterDepartamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Universidade Federal do Rio de Janeiro · BRStony Brook University · USNorthport VA Medical Center · US

Funding

New antifungals targeting the synthesis of fungal sphingolipidsR01AI116420 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI Maurizio Del Poeta · 2016 to 2026
$7.6M
Lipid-mediated fungal pathogenesisR01AI125770 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2016 to 2025
$6.2M
Sphingosine-1-phosphate and cryptococcosisR01AI136934 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2018 to 2022
$2.5M
BLRD VA I01 BX002624NIAID NIH HHS R01 AI116420NIAID NIH HHS R01 AI125770NIAID NIH HHS R01 AI136934
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiofilmsCell MembraneFatty Acids, MonounsaturatedMeperidineScedosporiumSphingolipids4-propionyloxy-4-phenyl-N-methylpiperidineFatty Acids, MonounsaturatedMeperidineSphingolipidsthermozymocidinantifungal drugsantifungal therapybiosynthetic pathwayglycosphingolipidsnew targetsScedosporium

Identifiers

PMID31713454
PMCPMC7270895
OpenAlexW2984142997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.