Evidence map›Paper›PMID 31713418›Full record

ArticleBiochemistry2019

The FeoC [4Fe-4S] Cluster Is Redox-Active and Rapidly Oxygen-Sensitive.

Aaron T Smith, Richard O Linkous, Nathan J Max, Alexandrea E Sestok, Veronika A Szalai, Kelly N Chacón

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. The structure of the full catalytic cycle ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Carbon upshift inmBio · 2025
    Article
  6. Article
  7. Article
  8. Structural Determinants ofbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Reconstitution of the Arginyltransferase (ATE1) Iron-Sulfur Cluster.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Article
  14. The structure of Vibrio cholerae FeoC reveals conservation of the helix-turn-helix motif but not the cluster-binding domain.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Metallomics : integrated biometal science · 2020
    Article
  19. Iron Acquisition by Bacterial Pathogens: Beyond Tris-Catecholate Complexes.Chembiochem : a European journal of chemical biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aaron T SmithDepartment of Chemistry and Biochemistry , University of Maryland, Baltimore County , Baltimore , Maryland 21250 United States.ORCID 0000-0002-9332-8683
Richard O LinkousDepartment of Chemistry and Biochemistry , University of Maryland, Baltimore County , Baltimore , Maryland 21250 United States.
Nathan J MaxDepartment of Chemistry and Biochemistry , University of Maryland, Baltimore County , Baltimore , Maryland 21250 United States.
Alexandrea E SestokDepartment of Chemistry and Biochemistry , University of Maryland, Baltimore County , Baltimore , Maryland 21250 United States.
Veronika A SzalaiPhysical Measurement Laboratory , National Institute of Standards and Technology , Gaithersburg , Maryland 20899 , United States.
Kelly N ChacónDepartment of Chemistry , Reed College , Portland , Oregon 97202 , United States.ORCID 0000-0003-1332-7283
University of Maryland, Baltimore County · USNational Institute of Standards and Technology · USReed College · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Graduate Training at The Chemistry Biology InterfaceT32GM066706 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L, SMITH, AARON T · 2004 to 2023
$3.3M
Deciphering the Mechanisms of Pathogenic Ferrous Iron Acquisition and Eukaryotic Post-Translational ArginylationR35GM133497 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI Aaron T Smith · 2019 to 2026
$2.9M
Intramural NIST DOC 9999-NISTNIGMS NIH HHS P41 GM103393NIGMS NIH HHS R35 GM133497NIGMS NIH HHS T32 GM066706
6 · The paper itself

Abstract

The acquisition of iron is essential to establishing virulence among most pathogens. Under acidic and/or anaerobic conditions, most bacteria utilize the widely distributed ferrous iron (Fe

Indexed as

Catalytic DomainElectron Spin Resonance SpectroscopyEscherichia coliEscherichia coli ProteinsIronIron-Binding ProteinsIron-Sulfur ProteinsKineticsOxidation-ReductionOxygenRepressor ProteinsSulfurEscherichia coli ProteinsFeoC protein, E coliIronIron-Binding ProteinsIron-Sulfur ProteinsOxygenRepressor ProteinsSulfur

Identifiers

PMID31713418
PMCPMC6904521
OpenAlexW2986388722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.