Evidence map›Paper›PMID 31713250›Full record

ArticleAllergy2020

Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample.

Annemarie G Hirsch, Cara Nordberg, Karen Bandeen-Roche, Bruce K Tan, Robert P Schleimer, Robert C Kern, Agnes Sundaresan, Jayant M Pinto, Thomas L Kennedy, Joseph Scott Greene and 2 more

Abstract read
In one paragraph

Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Incidentalomas in the head & neck.The British journal of radiology · 2023
    Review
  14. Article
  15. Progression of Rhinitis to Rhinosinusitis: A Cohort Study.ORL; journal for oto-rhino-laryngology and its related specialties · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Annemarie G HirschDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0001-7699-2171
Cara NordbergDepartment of Biomedical and Translational Informatics, Geisinger, Danville, Pennsylvania.
Karen Bandeen-RocheDepartment of Biostatistics, Johns Hopkins School of Public Health, Baltimore, Maryland.
Bruce K TanDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Robert P SchleimerDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Robert C KernDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Agnes SundaresanDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.
Jayant M PintoSection of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago Medicine, Chicago, Illinois.
Thomas L KennedyDepartment of Otolaryngology/Head and Neck/Facial Plastic Surgery, Geisinger, Danville, Pennsylvania.
Joseph Scott GreeneDepartment of Otolaryngology/Head and Neck/Facial Plastic Surgery, Geisinger, Danville, Pennsylvania.
Jordan R KuiperDepartment of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Brian S SchwartzDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0002-0739-9865

Funding

Population-based CRS epidemiology: sex differences, natural history, and long-term outcomes based on clinically-defined phenotypes and biologically-based endotypes - GeisingerP01AI145818 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2019 to 2023
$9.3M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2014 to 2017
$7.9M
Initiators, biomarkers and mechanisms of epithelial dysfunction and immune pathogenesis in chronic rhinosinusitis and aspirin exacerbated respiratory disease (AERD)R01AI137174 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2018 to 2022
$3.1M
NIAID NIH HHS P01 AI145818NIAID NIH HHS R01 AI137174NIAID NIH HHS U19 AI106683
6 · The paper itself

Abstract

backgroundChronic rhinosinusitis (CRS) epidemiology has been largely studied using symptom-based case definitions, without assessment of objective sinus findings.

objectiveTo describe radiologic sinus opacification and the prevalence of CRS, defined by the co-occurrence of symptoms and sinus opacification, in a general population-based sample.

methodsWe collected questionnaires and sinus CT scans from 646 participants selected from a source population of 200 769 primary care patients. Symptom status (CRS

resultsThe proportion of women with L-M scores ≥ 3, 4, or 6 (CRS

conclusionIn a general population-based sample in Pennsylvania, sinus opacification was more common among men than in women and opacification occurred in different locations by sex. Male sex, migraine headache, and prior sinus surgery were associated with higher odds of CRS

Indexed as

Paranasal SinusesRhinitisSinusitisAdolescentAdultAgedAged, 80 and overChronic DiseaseFemaleHumansInflammationMaleMiddle AgedPennsylvaniaYoung Adultchronic rhinosinusitisCT scanepidemiologysexsinus

Identifiers

PMID31713250
PMCPMC7176524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.