ReviewJournal of cancer education : the official journal of the American Association for Cancer Education2020
Overcoming Barriers: Evidence-Based Strategies to Increase Enrollment of Underrepresented Populations in Cancer Therapeutic Clinical Trials-a Narrative Review.
Review in Journal of cancer education : the official journal of the American Association for Cancer Education, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 63 citations in OpenAlex.
- Outreach to Native Hawaiian and Pacific Islander communities to increase breast cancer screening and clinical trial awareness.BMC cancer · 2026Article
- Practical approaches to inclusive recruitment practices in Parkinson's disease research.Journal of Parkinson's disease · 2026Article
- Article
- Factors associated with clinical research participation among Medicare beneficiaries with prostate cancer in the United States.Frontiers in oncology · 2026Article
- Design of a cluster randomized multi-level intervention to decrease barriers to minority cancer patient referral and enrollment to cancer clinical trials: The ACT WONDERContemporary clinical trials · 2025Article
- Strategies for recruiting participants underrepresented in clinical research: A scoping review.Social science & medicine (1982) · 2025Article
- A Formative Evaluation of Interventions to Enhance Clinical Trial Diversity Guided by the Socioecological Model.Cancers · 2025Article
- Article
- Unmasking Racial, Ethnic, and Socioeconomic Disparities in United States Chordoma Clinical Trials: Systematic Review.Cancers · 2025Review
- A multiphase recruitment approach to enroll Latinas diagnosed with cervical cancer into a qualitative study at an academic medical center in the Pacific Northwest.Journal of clinical and translational science · 2025Article
- How to optimize and evaluate diversity in gynecologic cancer clinical trials: statements from the GCIG Barcelona Meeting.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Impact of Clinical Trial Design on Recruitment of Racial and Ethnic Minorities.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024Article
- Diversity, Equity, and Inclusion in Multiple Myeloma: A Call to Action.Journal of the advanced practitioner in oncology · 2024Review
- Access to cancer clinical trials for racialised older adults: an equity-focused rapid scoping review protocol.BMJ open · 2024Article
- Outreach for Young Adult African Americans with Risk Factors for Stroke.Health literacy research and practice · 2024Article
- Enhancing Catchment Area Tools: A De-Identification Method for Integrating Clinical Trial Data with Cancer InFocus.Preventive oncology & epidemiology · 2024Article
- Barriers to Recruitment and Retention Among Underrepresented Populations in Cancer Clinical Trials: A Qualitative Study of the Perspectives of Clinical Trial Research Coordinating Staff at a Cancer Center.Journal of healthcare leadership · 2024Article
- Addressing disparities in cancer clinical trials: a roadmap to more equitable accrual.Frontiers in health services · 2024Article
- Article
- Interventions to improve access to clinical trials in urologic oncology.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Disparities in cancer incidence and mortality rates among racial and ethnic minorities (African Americans, Asian Americans, Pacific Islanders, American Indians, and Latinos/Hispanic Americans) in the USA are well documented. Enrollment of underrepresented populations in cancer therapeutic clinical trials, however, is very low. This is true despite federal mandates to ensure accrual rates adequate for analyses and the evidence that the effectiveness of specific therapies and medications varies across ethnic and racial groups. Consequently, cancer clinical decision-making is based on research studies where the majority of research participants are white males, despite the disproportionate cancer burden in racial and ethnic minority groups. To date, there have been multiple reviews detailing the barriers to enrollment for these populations in cancer clinical trials, but a notable lack of research on possible strategies to overcome them. The aim of this narrative review is to summarize the current evidence for effective approaches to increase enrollment of underrepresented minorities in cancer therapeutic clinical trials. These approaches include (1) cultural and linguistic adaptations of marketing materials, (2) the use of patient navigators, and (3) building ongoing community partnerships. The majority of studies reviewed employ multiple improvement strategies simultaneously. Identifying effective approaches to increase enrollment of underrepresented populations in cancer clinical trials is a critical step in reducing persistent disparities in cancer incidence and mortality among racial and ethnic populations.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.