ArticleJournal of neurology2020
Survival in treated idiopathic normal pressure hydrocephalus.
Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Clinical and Radiological Evolution of Idiopathic Normal Pressure Hydrocephalus: A Critical Review.Movement disorders clinical practice · 2026Review
- Survival After Shunt Therapy in Normal-Pressure Hydrocephalus: A Meta-Analysis of 1614 Patients.Neurology international · 2024Review
- Predicting the long-term course: Shunt surgery results in idiopathic normal pressure hydrocephalus-a comprehensive study.Acta neurochirurgica · 2024Article
- Deep learning assessment of disproportionately enlarged subarachnoid-space hydrocephalus in Hakim's disease or idiopathic normal pressure hydrocephalus.Radiology advances · 2024Article
- Peripheral immunity changes are associated with neurodegeneration and worse clinical outcome in idiopathic normal pressure hydrocephalus.European journal of neurology · 2024Article
- 10-year mortality, causes of death and cardiovascular comorbidities in idiopathic normal pressure hydrocephalus.Journal of neurology · 2024Article
- Automatic assessment of disproportionately enlarged subarachnoid-space hydrocephalus from 3D MRI using two deep learning models.Frontiers in aging neuroscience · 2024Article
- Evolution of neurodegeneration in patients with normal pressure hydrocephalus: a monocentric follow up study.Neurological research and practice · 2023Article
- Charlson comorbidity index applied to shunted idiopathic normal pressure hydrocephalus.Scientific reports · 2023Article
- Fluid dynamics in aging-related dementias.Neurobiology of disease · 2023Review
- Update on the Cognitive Presentations of iNPH for Clinicians.Frontiers in neurology · 2022Review
- Impacts of the COVID-19 Pandemic on the Healthcare Provision and Lived Experiences of Patients with Hydrocephalus.Journal of patient experience · 2022Article
- Intrathecal Contrast-Enhanced Magnetic Resonance Imaging of Cerebrospinal Fluid Dynamics and Glymphatic Enhancement in Idiopathic Normal Pressure Hydrocephalus.Frontiers in neurology · 2022Article
- Dual-Task Performance in Older Adults With and Without Idiopathic Normal Pressure Hydrocephalus.Frontiers in aging neuroscience · 2022Article
- Long term follow-up of shunted idiopathic normal pressure hydrocephalus patients: a single center experience.Acta neurologica Belgica · 2021Article
- 5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus.Journal of neurology · 2021Article
- Early shunt surgery improves survival in idiopathic normal pressure hydrocephalus.European journal of neurology · 2021Article
- Dynamic functional networks in idiopathic normal pressure hydrocephalus: Alterations and reversibility by CSF tap test.Human brain mapping · 2021Article
- Outcomes of Ventriculoperitoneal Shunt in Patients With Idiopathic Normal-Pressure Hydrocephalus 2 Years After Surgery.Frontiers in surgery · 2021Article
- Wide temporal horns are associated with cognitive dysfunction, as well as impaired gait and incontinence.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveTo describe survival and causes of death in 979 treated iNPH patients from the Swedish Hydrocephalus Quality Registry (SHQR), and to examine the influence of comorbidities, symptom severity and postoperative outcome.
methodsAll 979 patients operated for iNPH 2004-2011 and registered in the SHQR were included. A matched control group of 4890 persons from the general population was selected by Statistics Sweden. Data from the Swedish Cause of Death Registry was obtained for patients and controls.
resultsAt a median 5.9 (IQR 4.2-8.1) year follow-up, 37% of the iNPH patients and 23% of the controls had died. Mortality was increased in iNPH patients by a hazard ratio of 1.81, 95% CI 1.61-2.04, p < 0.001. More pronounced symptoms in the preoperative ordinal gait scale and the Mini-mental State Examination were the most important independent predictors of mortality along with the prevalence of heart disease. Patients who improved in both the gait scale and in the modified Rankin Scale postoperatively (n = 144) had a similar survival as the general population (p = 0.391). Deaths due to cerebrovascular disease or dementia were more common in iNPH patients, while more controls died because of neoplasms or disorders of the circulatory system.
conclusionsMortality in operated iNPH patients is 1.8 times increased compared to the general population, a lower figure than previously reported. The survival of iNPH patients who improve in gait and functional independence is similar to that of the general population, indicating that shunt surgery for iNPH, besides improving symptoms and signs, can normalize survival.
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