Evidence map›Paper›PMID 31712975›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2019

[New developments in topical pharmaceuticals].

Johannes Wohlrab

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Johannes WohlrabInstitut für angewandte Dermatopharmazie, Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle (Saale), Deutschland. johannes.wohlrab@medizin.uni-halle.de.
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Topical preparations are by far the most frequently used therapeutic or prophylactic pharmaceuticals by dermatologists. Although only a few new active ingredients in topical pharmaceuticals have reached the market in recent years, some innovative galenic concepts and strategies considering the intrinsic effect of topical preparations have been developed, and it is quite certain that we can count on more genuine innovations in the near future. In particular small molecules, but also biological drugs, can be expected to be delivered by topical preparations, especially for inflammatory diseases. Also, we await innovative strategies for the substitution or regulation of the physicochemical and microbiological barrier function of the skin, including completely new options relating to the application of ribonucleic acid derivatives or their inhibitors aiming at influencing gene expression. Overall, it can be stated that the potential of epicutaneous application will take shape in modern vehicle strategies and procedures that deploy the intrinsic effect of topical preparations and that progress in biotechnology and physical chemistry will become increasingly relevant in practice.

Indexed as

Administration, TopicalPharmaceutical PreparationsSkinPharmaceutical PreparationsEpicutaneous adminstrationPharmaceutical vehicle strategiesProphylaxisTherapyTopical drug administration

Identifiers

PMID31712975
OpenAlexW2986705280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.