ArticlePediatric cardiology2020
Frequent Ventricular Premature Beats in Children and Adolescents: Natural History and Relationship with Sport Activity in a Long-Term Follow-Up.
Article in Pediatric cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Premature ventricular contraction-induced ventricular dysfunction in children without structural heart disease: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Pooled it
- Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Spontaneous resolution of idiopathic ventricular arrhythmias in children: clinical predictors and a probability-based scoring system.European journal of pediatrics · 2026Article
- High Burden Ventricular Ectopy > 10% in Children with Structurally Normal Hearts: Investigating the Association of Ventricular Ectopy Frequency, Holter and ECG Findings, and Ventricular Dysfunction.Pediatric cardiology · 2025Article
- Arrhythmias in Pediatric Age: A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Assessment of palpitations in patients with frequent premature ventricular contractions.Journal of cardiovascular electrophysiology · 2025Article
- Efficacy and safety of radiofrequency catheter ablation in younger children with ventricular arrhythmias.Frontiers in pediatrics · 2025Article
- Case Report: High efficacy of low-dose flecainide as an add-on therapy to a beta-blocker for treating a high burden of idiopathic ventricular arrhythmias in a juvenile athlete.Frontiers in cardiovascular medicine · 2025Article
- Case Series: Genetic mimics of hypertrophic cardiomyopathy in elderly.Frontiers in cardiovascular medicine · 2025Article
- The Prognosis of Idiopathic Premature Ventricular Beats in Children with Structurally Normal Hearts.Turkish archives of pediatrics · 2024Article
- Older Age as a Predictor of Ongoing Active Changes in Follow-Up Cardiac Magnetic Resonance in Children with Acute Myocarditis.Journal of clinical medicine · 2024Article
- Clinical Significance of Whole-Body Computed Tomography Scans in Pediatric Out-of-Hospital Cardiac Arrest Patients Without Prehospital Return of Spontaneous Circulation.Diseases (Basel, Switzerland) · 2024Article
- The Relationship between Depression Symptoms and Physical Activity in Children with Idiopathic Ventricular Extrasystoles.Medicina (Kaunas, Lithuania) · 2024Article
- Advancements in the diagnosis and management of premature ventricular contractions in pediatric patients.Frontiers in pediatrics · 2024Review
- Ventricular arrhythmias recorded on 12-lead ambulatory electrocardiogram monitoring in healthy volunteer athletes and controls: what is common and what is not.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Ventricular Extrasystole in Children: Single-Center Experience.Turkish archives of pediatrics · 2023Article
- Moderator Band and Ventricular Tachycardia: Structural or Functional Substrate?Journal of cardiovascular development and disease · 2023Review
- Psychological Wellbeing and Perceived Fatigue in Competitive Athletes after SARS-CoV-2 Infection 2 Years after Pandemic Start: Practical Indications.Journal of functional morphology and kinesiology · 2022Article
- The Value of Continuous Electrocardiographic Monitoring in Pediatric Cardiology: A Local Center Experience.Cureus · 2022Article
- Incidental electrocardiogram abnormalities in children undergoing polysomnography.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Premature ventricular complexes (PVCs) are frequently documented in children. To date, few studies report long-term follow-up in pediatric cohorts presenting with frequent PVCs. The aim of this study is to assess the clinical relevance and long-term outcomes of frequent PVCs (≥ 500/24 h) in a large pediatric cohort. From 1996 to 2016, we enrolled all consecutive patients evaluated at Anna Meyer Children Hospital for frequent PVCs. Symptomatic children were excluded together with those patients with known underlying heart diseases; thus, our final cohort of study included 103 patients (male 66%; mean age 11 ± 3.4 years), with a mean follow-up of 9.5 ± 5.5 years. All patients were submitted to complete non-invasive cardiologic evaluation. The mean number of PVCs at Holter Monitoring (HM) was 11,479 ± 13,147/24 h; couplets and/or triplets were observed in 5/103 (4.8%) cases; 3 patients (2.9%) presented runs of non-sustained ventricular tachycardia (NSVT). High-burden PVCs (> 30,000/24 h) was confirmed in 11/103 (10.6%) patients. During the follow-up, only five patients (4.8%) developed clinical symptoms (3 for palpitations, 1 myocardial dysfunction due to frequent PVCs and NTSV; 1 arrhythmogenic cardiomyopathy); no deaths occurred. Basal PVCs were still present in 45/103 (43.7%) patients. Our data suggest that frequent PVCs may be addressed as a benign condition and should not preclude sport participation if not associated with cardiac malformations, heart dysfunction, or cardiomyopathy. This seems to be true also in presence of very frequent/high-burden PVCs. Otherwise, a careful follow-up is mandatory since sport eligibility should be reconsidered in case of onset of symptoms and/or ECG/echocardiographic changes.
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