Evidence map›Paper›PMID 31712801›Full record

ArticleAmerican journal of epidemiology2020

The Dynamic Relationship Between Asthma and Obesity in Schoolchildren.

Yue Zhang, Zhanghua Chen, Kiros Berhane, Robert Urman, Vaia Lida Chatzi, Carrie Breton, Frank D Gilliland

Open access · greenAbstract read
In one paragraph

Article in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Early childhood asthma and adiposity until adolescence: A prospective birth cohort study using body fat percentage.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  4. Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Obesity-related pediatric asthma: relationships between pulmonary function and clinical outcomes.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Article
  10. Article
  11. Association of fractional exhaled nitric oxide with asthma morbidity in urban minority children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Article
  12. Article
  13. Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Review
  14. Article
  15. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  16. Review
  17. Article
  18. The bidirectional association between wheezing and obesity during adolescence and the beginning of adulthood in the 1993 birth cohort, Pelotas, Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yue ZhangDepartment of Internal Medicine, Division of Epidemiology, School of Medicine, University of Utah, Salt Lake City, Utah.
Zhanghua ChenDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Kiros BerhaneDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Robert UrmanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Vaia Lida ChatziDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Carrie BretonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Frank D GillilandDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
University of Southern California · USUniversity of Utah · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
Utah Children's ProjectUH3OD023249 · OD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Christina Porucznik, JOSEPH BARNEY STANFORD · 2018 to 2026
$17.7M
Utah Children's ProjectUG3OD023249 · OD · UNIVERSITY OF UTAH · PI PORUCZNIK, CHRISTINA, STANFORD, JOSEPH BARNEY · 2016 to 2024
$9.4M
Urban Air Pollution &Persistent Early Life AsthmaP01ES009581 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILLILAND, FRANK D. · 1999 to 2010
$6.8M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory health (LA DREAMERs)UG3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN, GILLILAND, FRANK D. · 2016 to 2017
$6.5M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2013 to 2018
$4.0M
Project 2: Environmental Exposures, Stress, and Maternal Pregnancy-Related Weight OutcomesP50ES026086 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M · 2015 to 2019
$3.7M
NIEHS NIH HHS P01 ES009581NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P50 ES026086NIH HHS UG3 OD023249NIH HHS UG3 OD023287NIH HHS UH3 OD023249NIH HHS UH3 OD023287
6 · The paper itself

Abstract

Asthma and obesity are among the most prevalent chronic health conditions in children. Although there has been compelling evidence of co-occurrence of asthma and obesity, it is uncertain whether asthma contributes to the development of obesity or obesity contributes to the onset of asthma or both. In this study, we used a joint transition modeling approach with cross-lagged structure to understand how asthma and obesity influence each other dynamically over time. Subjects for this study included 5,193 kindergarten and first-grade students enrolled from 13 communities in 2002-2003 in the Southern California Children's Health Study, with up to 10 years of follow-up. We found that nonobese children with diagnosed asthma at a study visit were at 37% higher odds of becoming obese by the next annual visit compared with children without asthma (odds ratio = 1.38; 95% credible interval: 1.12, 1.71). However, the presence of obesity at the current visit was not statistically significantly associated with asthma onset in the next visit (odds ratio = 1.25; 95% credible interval: 0.94, 1.62). In conclusion, childhood asthma appears to drive an increase in the onset of obesity among schoolchildren, while the onset of obesity does not necessarily imply the future onset of asthma, at least in the short term.

Indexed as

AsthmaBody Mass IndexChildFemaleHumansMalePediatric ObesityPrevalenceSocioeconomic Factorsasthmajoint transition modelingobesityschoolchildren

Identifiers

PMID31712801
PMCPMC7443205
OpenAlexW2986627152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.