Evidence map›Paper›PMID 31712784›Full record

ArticleClinical oncology and research2019

Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma.

Cynthia Kassab, Daniel Zamler, Carlos Kamiya-Matsuoka, Zoran Gatalica, Joanne Xiu, David Spetzler, Amy B Heimberger

Open access · goldAbstract read
In one paragraph

Article in Clinical oncology and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Targeted therapy of papillary craniopharyngioma.Medical oncology (Northwood, London, England) · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Histopathology of Parasellar Neoplasms.Neuroendocrinology · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cynthia KassabDepartments of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
Daniel ZamlerGenomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
Carlos Kamiya-MatsuokaNeuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Zoran GatalicaCaris Life Sciences, Phoenix, AZ.
Joanne XiuCaris Life Sciences, Phoenix, AZ.
David SpetzlerCaris Life Sciences, Phoenix, AZ.
Amy B HeimbergerDepartments of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Modulation of Microglia and T Cell Interactions in Malignant GliomaR01CA120813 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HEIMBERGER, AMY BETH, RAO, GANESH · 2007 to 2025
$4.7M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA120813
6 · The paper itself

Abstract

Craniopharyngioma is a rare tumor in adults. Although histologically benign, it can be locally aggressive and may require additional therapeutic modalities to surgical resection. Analyses including next generation sequencing, chromogenic and

Indexed as

CraniopharyngiomaEGFRgenetic profilingimmune profilingPD-L1

Identifiers

PMID31712784
PMCPMC6844364
OpenAlexW2954272237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.