Evidence map›Paper›PMID 31712706›Full record

ArticleScientific reports2019

Mild chronic perturbation of inhibition severely alters hippocampal function.

Min-Yu Sun, Luke Ziolkowski, Peter Lambert, Hong-Jin Shu, Micah Keiser, Nicholas Rensing, Natasha Warikoo, Monika Martinek, Carson Platnick, Ann Benz and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. GABAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Non-sedative cortical EEG signatures of allopregnanolone and functional comparators.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Min-Yu SunDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Luke ZiolkowskiDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Peter LambertDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.ORCID http://orcid.org/0000-0001-9427-638X
Hong-Jin ShuDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Micah KeiserDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Nicholas RensingDepartment of Neurology, Washington University School of Medicine, St. Louis, USA.
Natasha WarikooDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Monika MartinekDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Carson PlatnickDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Ann BenzDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
John BracamontesDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, USA.
Gustav AkkDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, USA.
Joe Henry SteinbachDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, USA.
Charles F ZorumskiDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
Michael WongDepartment of Neurology, Washington University School of Medicine, St. Louis, USA.
Steven MennerickDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA. menneris@wustl.edu.ORCID http://orcid.org/0000-0003-0868-0664
Washington University in St. Louis · US

Funding

NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
SYNERGISTIC ACTIONS OF INTRAVENOUS ANESTHETICSR01GM108580 · NIGMS · WASHINGTON UNIVERSITY · PI AKK, GUSTAV · 2014 to 2021
$2.4M
A CHEMOGENETIC EVALUATION OF DELTA SUBUNIT EXCLUSION FROM GABA SYNAPSESR21MH111461 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2016 to 2017
$419k
Chemogenetic analysis of ethanol's selectivity for GABAA receptor populationsR21AA026753 · NIAAA · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2019 to 2020
$410k
NEUROSTEROIDS AND ANXIETY RELATED NETWORK FUNCTIONR21MH104506 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2014 to 2015
$406k
NEUROSTEROIDS & PROXIMAL INHIBITION IN THE HIPPOCAMPUSR21MH114866 · NIMH · WASHINGTON UNIVERSITY · PI ZORUMSKI, CHARLES F · 2018 to 2018
$234k
NIAAA NIH HHS R21 AA026753NICHD NIH HHS U54 HD087011NIGMS NIH HHS R01 GM108580NIGMS NIH HHS T32 GM007200NIMH NIH HHS R21 MH104506NIMH NIH HHS R21 MH111461NIMH NIH HHS R21 MH114866U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) T32GM007200
6 · The paper itself

Abstract

Pentameric GABA

Indexed as

Neural InhibitionAnimalsBiomarkersCell LineDiazepamDisease SusceptibilityElectroencephalographyExcitatory Postsynaptic Potentialsgamma-Aminobutyric AcidHippocampusHumansImmunohistochemistryInhibitory Postsynaptic PotentialsMiceMice, KnockoutReceptors, GABA-ABiomarkersDiazepamgamma-Aminobutyric AcidReceptors, GABA-A

Identifiers

PMID31712706
PMCPMC6848214
OpenAlexW2984066934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.