Evidence map›Paper›PMID 31712647›Full record

ArticleScientific reports2019

Progressive loss of muscle mass could be an adverse prognostic factor of 28-day mortality in septic shock patients.

Dong-Woo Seo, Kyung Won Kim, Chang Hwan Sohn, Seung Mok Ryoo, Youn-Jung Kim, Ahn Shin, Won Young Kim

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Sarcopenia and Mortality Risk of Patients with Sepsis: A Meta-Analysis.International journal of clinical practice · 2022
    Pooled it
  5. Article
  6. Article
  7. Review
  8. Myostatin deficiency not only prevents muscle wasting but also improves survival in septic mice.American journal of physiology. Endocrinology and metabolism · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong-Woo SeoDepartment of Biomedical Informatics, University of California San Diego, School of Medicine, La Jolla, USA.ORCID http://orcid.org/0000-0001-8104-0247
Kyung Won KimDepartment of Radiology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea.
Chang Hwan SohnDepartment of Emergency Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea.
Seung Mok RyooDepartment of Emergency Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea.
Youn-Jung KimDepartment of Emergency Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea.
Ahn ShinDepartment of Emergency Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea.
Won Young KimDepartment of Emergency Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea. wonpia73@naver.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A decrease in skeletal muscle mass has been shown to increase hospital mortality. Nevertheless, little is known about the association between progressive muscle loss over time and clinical outcomes. We aimed to evaluate whether progressive loss of muscle mass in septic shock patients was associated with mortality. We reviewed prospectively enrolled registry of septic shock which had 817 consecutive patients. Of these, 175 patients who had computed tomography (CT) at a time of admission as well as 3-6 months prior to admission were included. Between these two CTs, the change in total abdominal muscle area index (TAMAI) was evaluated for progressive muscle loss. The change in TAMAI was higher in the non-survivors (-7.6 cm

Indexed as

AgedFemaleFollow-Up StudiesHospitalizationHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedMuscular DiseasesPrognosisProspective StudiesRetrospective StudiesShock, SepticSurvival Rate

Identifiers

PMID31712647
PMCPMC6848164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.