Evidence map›Paper›PMID 31712090›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Assessment of readiness to transition from antenatal HIV surveillance surveys to PMTCT programme data-based HIV surveillance in South Africa: The 2017 Antenatal Sentinel HIV Survey.

Selamawit A Woldesenbet, Tendesayi Kufa, Peter Barron, Kassahun Ayalew, Mireille Cheyip, Brian C Chirombo, Carl Lombard, Samuel Manda, Yogan Pillay, Adrian J Puren

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  14. HIV Associated Preeclampsia: A Multifactorial Appraisal.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Selamawit A WoldesenbetCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: selamawitw@nicd.ac.za.
Tendesayi KufaCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Peter BarronSchool of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Kassahun AyalewStrategic Information Unit, Centers for Disease Control and Prevention, Pretoria, South Africa.
Mireille CheyipStrategic Information Unit, Centers for Disease Control and Prevention, Pretoria, South Africa.
Brian C ChiromboHIV and Hepatitis Program, World Health Organization, Pretoria, South Africa.
Carl LombardBiostatistics Unit, South African Medical Research Council, Cape Town, South Africa.
Samuel MandaBiostatistics Unit, South African Medical Research Council, Pretoria, South Africa.
Yogan PillayHIV & AIDS, TB and Maternal, Child and Women's Health (MCWH), National Department of Health, Pretoria, South Africa.
Adrian J PurenCenter for HIV and STI, National Institute for Communicable Diseases, Johannesburg, South Africa; Virology Department, University of the Witwatersrand, Johannesburg, South Africa.

Funding

Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

objectiveSouth Africa has used antenatal HIV surveys for HIV surveillance in pregnant women since 1990. We assessed South Africa's readiness to transition to programme data based antenatal HIV surveillance with respect to PMTCT uptake, accuracy of point-of-care rapid testing (RT) and selection bias with using programme data in the context of the 2017 antenatal HIV survey.

methodsBetween 1 October and 15 November 2017, the national survey was conducted in 1,595 public antenatal facilities selected using stratified multistage cluster sampling method. Results of point-of-care RT were obtained from medical records. Blood samples were taken from eligible pregnant women and tested for HIV using immunoassays (IA) in the laboratory. Descriptive statistics were used to report on: PMTCT uptake; agreement between HIV point-of-care RT and laboratory-based HIV-1 IA; and selection bias associated with using programme data for surveillance.

resultsPMTCT HIV testing uptake was high (99.8%). The positive percent agreement (PPA) between RT and IA was lower than the World Health Organization (WHO) benchmark (97.6%) at 96.3% (95% confidence interval (CI): 95.9%-96.6%). The negative percent agreement was above the WHO benchmark (99.5%), at 99.7% (95% CI: 99.6%-99.7%) nationally. PPA markedly varied by province (92.9%-98.3%). Selection bias due to exclusion of participants with no RT results was within the recommended threshold at 0.3%.

conclusionFor the three components assessed, South Africa was close to meeting the WHO standard for transitioning to routine RT data for antenatal HIV surveillance. The wide variations in PPA across provinces should be addressed.

Indexed as

Population SurveillanceAdolescentAdultClinical Laboratory TechniquesFemaleHIV-1HIV InfectionsHumansInfectious Disease Transmission, VerticalMiddle AgedPoint-of-Care TestingPregnancyPregnancy Complications, InfectiousPrenatal CareSouth AfricaWorld Health OrganizationPMTCTPregnant womenRapid testingSouth AfricaSurveillanceTest agreement

Identifiers

PMID31712090
PMCPMC8767461

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.