ArticleBrain stimulation
SICI during changing brain states: Differences in methodology can lead to different conclusions.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Dynamics of cortical excitability in stimulus-response mapping for overt and covert movements is locked to visual stimulus: an LRP-TMS study.Experimental brain research · 2026Article
- GABAergic and glutamatergic mechanisms of cortical excitability shape motor resonance during action observation as measured by transcranial magnetic stimulation.Frontiers in human neuroscience · 2026Article
- The relationship between corticospinal excitability and behavioural measures of movement imagery ability.Brain communications · 2026Article
- Cortical Excitability as a Prognostic and Phenotypic Stratification Biomarker in Amyotrophic Lateral Sclerosis.Annals of neurology · 2025Article
- Motor Cortex Disinhibition Correlates with Olfactory Dysfunction in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Review
- Relationship between transcranial magnetic stimulation markers of motor control and clinical recovery in obsessive compulsive disorder/Gilles de la Tourette syndrome: a proof of concept case study.Frontiers in psychiatry · 2024Article
- Motor potentials evoked by transcranial magnetic stimulation: interpreting a simple measure of a complex system.The Journal of physiology · 2023Review
- The recruitment of indirect waves within primary motor cortex during motor imagery: A directional transcranial magnetic stimulation study.The European journal of neuroscience · 2022Article
- Inter-Individual Variability in Motor Output Is Driven by Recruitment Gain in the Corticospinal Tract Rather Than Motor Threshold.Brain sciences · 2022Article
- Action Selection and Motor Decision Making: Insights from Transcranial Magnetic Stimulation.Brain sciences · 2022Review
- Contribution of TMS and TMS-EEG to the Understanding of Mechanisms Underlying Physiological Brain Aging.Brain sciences · 2021Review
- Influence of Voluntary Contraction Level, Test Stimulus Intensity and Normalization Procedures on the Evaluation of Short-Interval Intracortical Inhibition.Brain sciences · 2020Article
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Authors and funding
4 authors.
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Abstract
backgroundShort-latency intracortical inhibition (SICI) is extensively used to probe GABAergic inhibitory mechanisms in M1. Task-related changes in SICI are presumed to reflect changes in the central excitability of GABAergic pathways. Usually, the level of SICI is evaluated using a single intensity of conditioning stimulus so that inhibition can be compared in different brain states.
objectiveHere, we show that this approach may sometimes be inadequate since distinct conclusions can be drawn if a different CS intensity is used.
methodsWe measured SICI using a range of CS intensities at rest and during a warned simple reaction time task.
conclusionsOur results show that SICI changes that occurred during the task could be either larger or smaller than at rest depending on the intensity of the CS. These findings indicate that careful interpretation of results are needed when a single intensity of CS is used to measure task-related physiological changes.
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