Evidence map›Paper›PMID 31711755›Full record

ArticleStructure (London, England : 1993)2020

Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.

Brianna J Klein, Khan L Cox, Suk Min Jang, Jacques Côté, Michael G Poirier, Tatiana G Kutateladze

Open access · bronzeAbstract read
In one paragraph

Article in Structure (London, England : 1993), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. High-Affinity Peptide-Drug Conjugate Ligands for the TRIM24 PHD and Bromodomain.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. HBO1, a MYSTerious KAT and its links to cancer.Biochimica et biophysica acta. Gene regulatory mechanisms · 2024
    Review
  11. Article
  12. Guiding the HBO1 complex function through the JADE subunit.Nature structural & molecular biology · 2024
    Article
  13. Article
  14. Non-histone binding functions of PHD fingers.Trends in biochemical sciences · 2023
    Review
  15. Article
  16. Article
  17. Mosaicism inCase reports in genetics · 2023
    Article
  18. Histone Readers and Their Roles in Cancer.Cancer treatment and research · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Brianna J KleinDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Khan L CoxDepartment of Physics, Ohio State University, Columbus, OH 43210, USA.
Suk Min JangLaval University Cancer Research Center, CHU de Québec-UL Research Center-Oncology Division, Quebec City, QC G1R 3S3, Canada.
Jacques CôtéLaval University Cancer Research Center, CHU de Québec-UL Research Center-Oncology Division, Quebec City, QC G1R 3S3, Canada.
Michael G PoirierDepartment of Physics, Ohio State University, Columbus, OH 43210, USA. Electronic address: poirier.18@osu.edu.
Tatiana G KutateladzeDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: tatiana.kutateladze@cuanschutz.edu.
The Ohio State University · USUniversité Laval · CAUniversity of Colorado Denver · US

Funding

Dissecting functional cooperation among subunits in a catalytic ribonucleoproteinR01GM120582 · NIGMS · OHIO STATE UNIVERSITY · PI GOPALAN, VENKAT · 2016 to 2019
$1.9M
Molecular mechanism of chromatin targeting by BRPF1R01GM100907 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI KUTATELADZE, TATIANA G · 2015 to 2018
$1.4M
Understanding how two related mammalian histone acetyl transferase co-activators, SAGA and ATAC, differentially regulate chromatin dynamics and transcriptionR01GM131626 · NIGMS · OHIO STATE UNIVERSITY · PI POIRIER, MICHAEL GUY · 2019 to 2021
$1.3M
Interdomain crosstalk in MORC3R01GM125195 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI KUTATELADZE, TATIANA G · 2017 to 2021
$1.3M
Regulatory Mechanisms of Linker Histones and Their Post-Translational ModificationsR01GM121966 · NIGMS · OHIO STATE UNIVERSITY · PI POIRIER, MICHAEL GUY · 2017 to 2020
$1.2M
CIHR FDN-143314NIGMS NIH HHS R01 GM100907NIGMS NIH HHS R01 GM120582NIGMS NIH HHS R01 GM121966NIGMS NIH HHS R01 GM125195NIGMS NIH HHS R01 GM131626
6 · The paper itself

Abstract

The assembly of human histone acetyltransferase MOZ/MORF complexes relies on the scaffolding bromodomain plant homeodomain (PHD) finger 1 (BRPF1) subunit. The PHD-zinc-knuckle-PHD module of BRPF1 (BRPF1

Indexed as

Adaptor Proteins, Signal TransducingBromodomain Containing ProteinsCatalytic DomainChromatinCrystallography, X-RayDNADNA-Binding ProteinsHistonesHumansProtein BindingProtein DomainsAdaptor Proteins, Signal TransducingBromodomain Containing ProteinsBRPF1 protein, humanChromatinDNADNA-Binding ProteinsHistonesBRPF1chromatinDNAhistoneMORFMOZPZP

Identifiers

PMID31711755
PMCPMC6949404
OpenAlexW2985439614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.