Evidence map›Paper›PMID 31711553›Full record

ArticleEpidemiology and infection2019

An outbreak of hepatitis A in Canada: The use of a control bank to conduct a case-control study.

C R Smith, T Kershaw, K Johnson, K Meghnath

Abstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Hepatitis A outbreak associated with food consumption and sexual practices: a case-control study, Curitiba, Paraná, 2024.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C R SmithOutbreak Management Division, Public Health Agency of Canada, Guelph, Ontario, Canada.ORCID 0000-0002-3051-0437
T KershawOutbreak Management Division, Public Health Agency of Canada, Guelph, Ontario, Canada.
K JohnsonEnteric, Zoonotic and Vectorborne Disease Unit, Public Health Ontario, Toronto, Ontario, Canada.
K MeghnathEnteric, Zoonotic, Vectorborne and Environmental Infections Program, BC Centre for Disease Control, Vancouver, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An outbreak of 18 cases of hepatitis A virus infection across five Canadian provinces was investigated. Case onsets occurred between October 2017 and May 2018. A retrospective matched case-control study was conducted to identify the likely source of the outbreak. Three matched controls were recruited for each case using a previously established control bank, supplemented by landline and cell phone call lists. Univariate and multivariate matched analyses were conducted to identify a potential outbreak source. Seventy-two per cent of controls were recruited through the control bank, and required on average 25.5 calls per recruited control; 20% of controls were recruited through a landline sample and 8% of controls were recruited through a cell phone sample, requiring an average of 847.3 and 331.7 calls per recruited control, respectively. Results of the analysis pointed to shrimp/prawns (odds ratio (OR) 15.75, p = 0.01) and blackberries (OR 7.21, p = 0.02) as foods of interest, however, an outbreak source could not be confirmed. The control bank proved to be a more efficient method for control recruitment than random call lists. Expanding the control bank size and using alternative methods, such as online surveys, may prove beneficial for increasing the timeliness of a case-control study during an outbreak investigation.

Indexed as

Disease OutbreaksAdolescentAdultAgedAged, 80 and overCanadaCase-Control StudiesChildChild, PreschoolFemaleFood MicrobiologyHepatitis AHumansInfantInfant, NewbornMalecase-control studyHepatitis Aoutbreaks

Identifiers

PMID31711553
PMCPMC6873153

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.