Evidence map›Paper›PMID 31711539›Full record

ArticleJournal of biomedical semantics2019

Text mining brain imaging reports.

Beatrice Alex, Claire Grover, Richard Tobin, Cathie Sudlow, Grant Mair, William Whiteley

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. A Large Language Model to Detect Negated Expressions in Radiology Reports.Journal of imaging informatics in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beatrice AlexSchool of Informatics, University of Edinburgh, Informatics Forum, 10 Crichton Street, Edinburgh, UK. balex@ed.ac.uk.
Claire GroverSchool of Informatics, University of Edinburgh, Informatics Forum, 10 Crichton Street, Edinburgh, UK.
Richard TobinSchool of Informatics, University of Edinburgh, Informatics Forum, 10 Crichton Street, Edinburgh, UK.
Cathie SudlowCentre for Medical Informatics, University of Edinburgh, 9 Little France Road, Edinburgh, UK.
Grant MairCentre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK.
William WhiteleyCentre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK.

Funding

Chief Scientist Office SCAF/17/01Medical Research Council G0902303Medical Research Council MC_PC_17209Medical Research Council MR/L023784/1Medical Research Council MR/L023784/2
6 · The paper itself

Abstract

backgroundWith the improvements to text mining technology and the availability of large unstructured Electronic Healthcare Records (EHR) datasets, it is now possible to extract structured information from raw text contained within EHR at reasonably high accuracy. We describe a text mining system for classifying radiologists' reports of CT and MRI brain scans, assigning labels indicating occurrence and type of stroke, as well as other observations. Our system, the Edinburgh Information Extraction for Radiology reports (EdIE-R) system, which we describe here, was developed and tested on a collection of radiology reports.The work reported in this paper is based on 1168 radiology reports from the Edinburgh Stroke Study (ESS), a hospital-based register of stroke and transient ischaemic attack patients. We manually created annotations for this data in parallel with developing the rule-based EdIE-R system to identify phenotype information related to stroke in radiology reports. This process was iterative and domain expert feedback was considered at each iteration to adapt and tune the EdIE-R text mining system which identifies entities, negation and relations between entities in each report and determines report-level labels (phenotypes).

resultsThe inter-annotator agreement (IAA) for all types of annotations is high at 96.96 for entities, 96.46 for negation, 95.84 for relations and 94.02 for labels. The equivalent system scores on the blind test set are equally high at 95.49 for entities, 94.41 for negation, 98.27 for relations and 96.39 for labels for the first annotator and 96.86, 96.01, 96.53 and 92.61, respectively for the second annotator.

conclusionAutomated reading of such EHR data at such high levels of accuracies opens up avenues for population health monitoring and audit, and can provide a resource for epidemiological studies. We are in the process of validating EdIE-R in separate larger cohorts in NHS England and Scotland. The manually annotated ESS corpus will be available for research purposes on application.

Indexed as

Data MiningNeuroimagingResearch ReportBrainElectronic Health RecordsHumansNatural Language ProcessingElectronic healthcare recordsNeuroimaging reportsStroke classificationText mining

Identifiers

PMID31711539
PMCPMC6849161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.